Study of Thyroid Dysfunction in the Elderly
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 7
Abstract
Back ground: In older adults there is a reduction in pituitary sensitivity to thyroid hormones (altered set point), higher production of isoforms with lower biological activity and reduced functional capacity of thyroid with age. Aim: To evaluate thyroid function in the older age group and identify the most common form of thyroid dysfunction. Materials and Methods: Retrospective evaluation of records of patients who attended department of Nuclear Medicine, KGH from January to December of 2014 was conducted. They were assessed for thyroid function by Radioimmunoassay of T3, T4,TSH hormones. Results: 35.6% were men and 64.38% were women in the age group of 60-85 yrs. Mean age was 66.16± 11yrs. 57.5% were Euthyroid 12.3% were Hypo thyroid, 21.9% were marked as Subclinical hypothyroid. 2.73% were hyperthyroid and 5.47% had sub-clinical hyperthyroid. In Euthyroid individuals, 60-69 Yrs mean serum thyroid stimulating hormone ( S.TSH )levels were 2.28 and 1.29 in 70-85 yrs, P<0.05 was statistically significant. In men mean S.TSH was 2.4±0.97 µIU/ml and women 2.6±0.93 µIU/ml, P>0.05 the gender variation was not significant. Conclusion: Subclinical hypothyroidism was the more prevalent form of thyroid dysfunction in 60-69 yrs age group, women were more affected, there was no statistically significant gender variation in various types of thyroid dysfunction. S.TSH levels showed an inverse relationship with increasing age.
Authors and Affiliations
Dr Madhuri Sepuri, Dr A Lakshmi Kantham, Dr Basumitra Das
Keywords
Related Articles
- EP ID EP377272
- DOI 10.9790/0853-1707042023.
- Views 53
- Downloads 0
“Determination of potential virulence factors in clinical isolates of various Candida species to assess its clinical implication in a tertiary care hospital in Eastern India”.
Candidiasis is the commonest fungal disease in human caused by various species of the yeast like fungi belonging to the genus Candida. It is commonly encountered as an endogenous infection due to its commensal nature. Tr...
Comparison of Open Reduction- Internal Fixation of Proximal Hummers Interlocking System (PHILOS) Versus Closed Reduction and K-Wire Fixation in Proximal Humeral Fracture.
Fracture proximal humerus is the 2nd most common fracture of upper limb in adults. This fracture is treated by ORIF by PHILOS and percutaneous k wire fixation. Objective:To compare the result of both techniques Methods:...
“Study of Impact of Yoga on Physiological And Biochemical Parameters in Hypertensive And Normal Subjects.’’
Stress is found to be an important factor in the etiology or precipitation of hypertension. Yoga controls the stress. In the present study we aim to study the degree of effect that yoga brings in normal subjects as compa...
An Analysis of CNS Tumors in Squash Preparations with Histological Correlation
Background: Squash cytologyis now a well establishedand universally accepted techniquein diagnosing a wide range of CNS lesions and is currently employed for both therapeutic and prognostic reasons. Aims and Objectives:...
Dabigatran (Pradaxa) Induced Liver Injury (Case Presentation)
Dabigatran is a novel antithrombin anticoagulant that was approved by the FDA in 2010 to be used for the prevention of stroke and venous embolism in patients with chronic atrial fibrillation. In this article, we present...