Study of Thyroid Dysfunction in the Elderly
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 7
Abstract
Back ground: In older adults there is a reduction in pituitary sensitivity to thyroid hormones (altered set point), higher production of isoforms with lower biological activity and reduced functional capacity of thyroid with age. Aim: To evaluate thyroid function in the older age group and identify the most common form of thyroid dysfunction. Materials and Methods: Retrospective evaluation of records of patients who attended department of Nuclear Medicine, KGH from January to December of 2014 was conducted. They were assessed for thyroid function by Radioimmunoassay of T3, T4,TSH hormones. Results: 35.6% were men and 64.38% were women in the age group of 60-85 yrs. Mean age was 66.16± 11yrs. 57.5% were Euthyroid 12.3% were Hypo thyroid, 21.9% were marked as Subclinical hypothyroid. 2.73% were hyperthyroid and 5.47% had sub-clinical hyperthyroid. In Euthyroid individuals, 60-69 Yrs mean serum thyroid stimulating hormone ( S.TSH )levels were 2.28 and 1.29 in 70-85 yrs, P<0.05 was statistically significant. In men mean S.TSH was 2.4±0.97 µIU/ml and women 2.6±0.93 µIU/ml, P>0.05 the gender variation was not significant. Conclusion: Subclinical hypothyroidism was the more prevalent form of thyroid dysfunction in 60-69 yrs age group, women were more affected, there was no statistically significant gender variation in various types of thyroid dysfunction. S.TSH levels showed an inverse relationship with increasing age.
Authors and Affiliations
Dr Madhuri Sepuri, Dr A Lakshmi Kantham, Dr Basumitra Das
Keywords
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- EP ID EP377272
- DOI 10.9790/0853-1707042023.
- Views 42
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