Study of Thyroid Profile in Patients with Type 2 Diabetes Mellitus
Journal Title: INTERNATIONAL JOURNAL OF SCIENTIFIC STUDY - Year 2017, Vol 5, Issue 2
Abstract
Background: Diabetes mellitus (DM), a common endocrine metabolic disorder, is an important cause of morbidity and mortality worldwide. Patients with diabetes have a higher prevalence of thyroid disorders when compared with general population. Alteration in thyroid function complicates the management of DM and its complications. Materials and Methods: This study was conducted from June 2015 to June 2016 in Medicine Department of Mahatma Gandhi Memorial Hospital, Warangal. 108 patients with known Type 2 DM or newly detected cases were included in the study. All the patients were evaluated for thyroid dysfunction by testing thyroid profile (triiodothyronine, thyroxine, and thyroid-stimulating hormone). The correlation of prevalence of thyroid disorder with gender distribution, age distribution, hemoglobin A1C, duration of diabetes, hypertension, family history of diabetes, body mass index, usage of oral hypoglycemic agents and insulin, and dyslipidemia was then done. The observations and interpretations were recorded, and results obtained were statistically analyzed. Results: In this study, age of the patient ranges from 35 to 70 years with maximum number of patients between the age group 41 and 60 years. In our study, 13% of the patients with Type 2 DM had abnormal thyroid profile. Among abnormal thyroid profile, the most common abnormality was subclinical hypothyroidism (64.2%) followed by subclinical hyperthyroidism (21.4%) followed by overt hypothyroidism. The prevalence of thyroid abnormality is more common in females than in males. Our study showed a significant correlation between abnormal thyroid profile and family history of diabetes and serum lipid profile. Conclusion: The occurrence of thyroid dysfunction among Type 2 DM patients is very high (13%) with subclinical hypothyroidism is being most common. All patients with Type 2 DM should be screened for thyroid dysfunction to reduce the mortality rate.
Authors and Affiliations
Madavaram Sreelatha, V Suresh Kumar, G Chandra Shekar, V Chandra Shekar
Keywords
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