Study of Various Histopathological Lesions of Prostate and Their Correlation with Serum Prostate Specific Antigen.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 3
Abstract
Background: Carcinoma of the prostate is most common non skin cancer in the west and the second leading cause of cancer death among men. In India, carcinoma of prostate occupies 2nd to 10th rank among cancers in men. The present study includes description of incidence of various lesions of prostate, their clinical manifestations, serum PSA level, classification, and grading of prostate tumors. Methods: The present study was conducted 226 prostatic needle biopsies in Department of Pathology, S. P. Medical college, Bikaner. Materials for the study consisted of prostate needle biopsies. The section were examined for histomorphological characters of prostate and clinical history was taken. The PSA levels were estimated. After studying the histopathological features, the diagnosis of various types of prostatic lesions was made and Gleason’s scoring was done in cases of prostatic carcinoma. Subsequently, a correlation was made between the histopathological diagnosis and serum PSA level. Results: Disease was prevalent in 7th and 8th decade of life with most common type of lesion was benign followed by malignant. Majority of 55% of benign lesions were found to be associated with serum PSA level <4ng/ml and 31.5% malignant lesion were found to be associated with serum PSA level 20.1-40.0 ng/ml. Most common gleason score was 7. Conclusion: In conclusion benign prostatic hyperplasia is the most common pathology encountered in prostatic specimens. PSA is specific for prostatic tissue and is raised in both benign and malignant lesions of prostate.
Authors and Affiliations
Subhash Chandra Dhayal
Keywords
Related Articles
- EP ID EP541109
- DOI -
- Views 111
- Downloads 0
Ganciclovir use evaluation in kidney transplantation
Objective: In this study, we evaluated certain aspects of the usage and administration of one lifesaving, high cost medication, i.e., Ganciclovir for the prevention and treatment of cytomegalovirus (CMV) infection in tra...
Treatment of Mandibular Fractures with a Malleable Non-Compression Miniplate.
Background- Bone is a dynamic tissue and its basic function is to carry load and to support and protect organs. The strength & rigidity of bone are therefore its primary qualities. Methods- The study comprised of 15 pati...
Spinal Metastasis of Breast Cancer after 14 Years: A Rare Case Report
Breast cancer is a leading cause of mortality and morbidity in the developing as well as developed countries. The undermined pathophysiology is responsible for the diversity of presentation at the time of diagnosis, resp...
Inflammatory Markers of Pulmonary Expirate in Children with Airway Remodeling In Bronchial Asthma.
Goal: of research is to study in the dynamics the informative value of the oxidatively modified proteins level in a pulmonary expirate of the school-age patients with bronchial asthma, depending on the degree of bronchia...
Effectiveness of Ramosetron and Ondansetron for prevention of nausea and vomiting in elective lower segment caesarean section patients under Spinal Anaesthesia.
Aim & Objective : The aim of this study was to evaluate and compare the efficacy and safety of inj. ondansetron 4 mg and inj. ramosetron 0.3 mg administered intravenously as an antiemetic in patients undergoing elective...