Study of wound-dressing materials based on collagen, sodium carboxymethylcellulose and silver nanoparticles used for their antibacterial activity in burn injuries
Journal Title: Proceedings of the International Conference on Advanced Materials and Systems (ICAMS) - Year 2018, Vol 1, Issue
Abstract
There are 2 types of bacteria that can produce serious infections and in many cases they lead to intestinal infections, meningitis or even toxic shock syndrome: Escherichia coli (E.coli) and Staphyloccocus aureus (S.aureus) . They are the most common source of infection worldwide and it’s really necessary to understand their mecanism of action. The objective of this study was to develop and characterize wound-dressing materials based on collagen (COLL), sodium carboxymethylcellulose (CMC-Na) and silver nanoparticles (AgNPs) designed to be used for burn injuries. We chose to use a composite material because it has multiple desirable effects, both on the wound and against the bacteria. Type I fibrillar collagen gel was extracted from calf hide. Sodium carboxymethylcellulose was used because it’s biocompatible and non-toxic. Silver nanoparticles were used for their antimicrobial activity. Obtained wound-dressing material was characterized by FT-IR spectroscopy, scanning electronic microscopy, water up-take and degradation in collagenase solution. The results showed that this combination of materials is ideal for a faster healing of the wound and it considerably reduces the risk of infection.
Authors and Affiliations
Sorina-Alexandra Leau, Ştefania Marin, Gheorghe Coară, Luminiţa ALBU, Roxana CONSTANTINESCU, Mădălina Georgiana ALBU KAYA, Ionela-Andreea Neacşu
Keywords
Related Articles
- EP ID EP602502
- DOI 10.24264/icams-2018.I.18
- Views 128
- Downloads 0
Composite scaffolds for bone regeneration made of collagen/hydroxyapatite/eucalyptus essential oil
Bone regeneration is a serious problem nowadays because of the increased number of people suffering from infections, arthritis and bond loss. The aim of the present study was to develop and characterize collagen – hydrox...
LEAMAN - Manager in an efficient and innovative leather company
The leather industry, as a global industry, being highly dependent on access to raw materials and to export markets, is in a quickly changing business environment, which is particularly challenging for SME-dominated sect...
The status of leather supply chain in Egypt: an exploratory study for the INNOLEA project
Egypt has a traditional wealth in manufacture and use of leather and leather products as demonstrated on the walls of the tombs of pharaonic civilization. Nowadays the status of leather supply chain in Egypt has deterior...
Due diligence for healthy workplaces in the European tanning industry
Corporate Social Responsibility is vital to pursue the systemic changes needed within business and value chains to achieve the Sustainable Development Goals (https://www.un.org/ sustainabledevelopment/sustainable-develop...
FT-IR analysis of Fusarium oxysporum grown myco-composite
Present study was focused on obtaining a novel biocomposite obtained from a plant pathogenic strain, Fusarium oxysporum¸on wastes from renewable sources, and assessment of microbial development on both the substrate surf...