Study of Wound Healing Activity of Parthenium Hysterophorus by Excision Wound Model in Rats
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 2
Abstract
Fresh Parthenium hysterophorus was collected from the nearby area and was authenticated by local botanist of Science College. Aerial parts were shade dried and powdered in the department of pharmacology. The powder (Aerial parts) was macerated for 24 hours in 70 %v/v ethanol. The hydro-alcoholic extracts was obtained by percolation using 70 % v/v ethanol as a solvent. Percolated solution was again shade dried and extract was obtained for topical application Parthenium hysterophorus extract was mixed with simple ointment as mention below. In excision wound model, 5% ointment of PH extract showed reduction in wound area on 4th day which was not significant but 8th day onwards reduction in wound area was very significant (p <0.01) as compare to control. Whereas 10% ointment of PH extract and standard both showed reduction in wound area on 4th day onward which was highly significant (p <0.001) as compare to control.
Authors and Affiliations
Nishikant A. Ingole, Prafulla Pralhad Thaware, Sushil K Verma, Shailesh K Kawle, Ninad N Nagrale
Keywords
Related Articles
- EP ID EP540092
- DOI 10.21276/ijmrp.2018.4.2.070
- Views 70
- Downloads 0
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