STUDY ON THE PHYTOCHEMICAL AND ANTIOXIDANT PROPERTIES OF THE AERIAL PARTS OF FICUS HISPIDA LINN
Journal Title: World Journal of Pharmaceutical and life sciences - Year 2018, Vol 4, Issue 10
Abstract
Ficus hispida Linn. (F. hispida) is a small but well distributed species of tropical fig tree. Although it is used in traditional medicine for the treatment of many diseases, there is a lack of systemic reports on the phytochemical and antioxidant properties of the aerial parts of that plant. This study was undertaken to investigate the phytochemical and antioxidant properties of F. hispida fruits, leaves and bark (aerial parts) using four different solvents (methanol, ethanol, chloroform and n-hexane). Qualitative and quantitative analyses were done for the presence and content of phytochemicals. Six different in vitro assay models were used to investigate the antioxidant activity. Phytochemical screening confirmed the presence of alkaloids, flavonoids, flavonols, resins, saponins, proanthocyanidins, glycosides, steroids and tannins. Quantitative analysis demonstrated the total content of polyphenols such as phenolics, flavonoids, flavonols and proanthocyanidins in those extracts. Among all extracts, ethanol extract of F. hispida bark showed highest activity in total antioxidant capacity assay, whereas the methanol extract of F. hispida bark exhibited maximum activity in ferric reducing antioxidant power assay. In DPPH and Superoxide radical scavenging assays, ethanol extract of F. hispida bark showed highest scavenging activity among all extracts with the IC50 values of 41.56±2.68 μg/ml and 77.83±4.35 μg/ml respectively. In ABTS scavenging assay, methanol extract of F. hispida fruits exhibited maximum activity with IC50 value of 50.79±3.67 μg/ml and in Nitric Oxide radical scavenging assay, ethanol extract of F. hispida leaves exhibited the highest activity with IC50 value of 117.73±2.23 μg/ml.
Authors and Affiliations
Mohammad Amirul Islam
Keywords
Related Articles
- EP ID EP656371
- DOI -
- Views 144
- Downloads 0
PREVENTION AND MANAGEMENT OF OSTEOARTHRITIS: A REVIEW
In the science of life all the aspects of human being health are clearly mentioned. Due to changes in day-to-day life style, the superiority of human health is falling. Dreadful changes in life style have lead to disorde...
REVIEW OF PRAMEHA WITH SPECIAL REFERENCE TO AVYAYAM HETU
In Today’s era, Prameha disease is a big challenge in front of society and all healthcare systems. Due to reason of family history and other modern improper lifestyle, the number of Pramehi patients is gaining high. Over...
PCOS-TODAY’S LEADING SYNDROME
Polycystic ovarian syndrome is a common endocrine system disorder among women of reproductive age. Most women with PCOS have many small cysts in the ovaries. Hence, it is called Polycystic ovarian syndrome. Hyper-insulin...
ANTI TUBERCULOSIS INDUCED HEPATITIS
Objective: To determine the frequency of Anti Tuberculosis induced hepatitis. Methodology; In this descriptive case series study which was carried out at Medical Unit II, Sheikh Zayed Hospital, Rahim Yar Khan during Augu...
EVALUATION OF TETRACYCLINE ANTIBIOTIC RESISTANCE: RELATION OF ANTIBIOTIC QUALITY PARAMETERS TO CASES OF RESISTANCE OCCURRING IN ARIS DISEASE IN TASIKMALAYA CITY HEALTH CENTER
Objective. Tetracycline is an antibiotic that usually used in treatment of acute respiratory infections (ARIs). One of the factors that support the occurrence of cases of antibiotic resistance is the antibiotic quality p...