Study on weak D antigen (Du ) at a Tertiary Healthcare Center in Blood Donors of Tripura
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
Abstract: Introduction: The study on detection of weak RhD (Du ) antigen among 4200 healthy blood donors at Tripura Medical College & Dr BRAM Teaching Hospital blood blank associated from January 2015 to December 2016. Method: Blood samples that were negative for RhD by immediate spin tube method were tested for weak D by indirect antiglobulin test. Observation and results: Among 4200 healthy blood donors, 4060(96.67%) were RhD factor positive while, 140(3.33%) were Rhd negative. Among these, 140 RhD factor negative individuals 1 (0.007%) were weak D positive. Conclusion: Numerous studies conclude that weak D antigen is immunogenic and is capable of producing alloimmunisation if transfused to RhD negative subjects. Ergo, it is pertinent to also detect the Weak D or partial D status of those individuals who are negative with saline anti-D.
Authors and Affiliations
Dr. Debaprasad Chakraborty, Dr. Ramit Chakraborty, Dr. Sutanuka Khasnabish, Dr. Habibul Islam
Keywords
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- EP ID EP600255
- DOI 10.9790/0853-1603104142.
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