Study the Correlation between Anthropometric Parameters and Biochemical Cardiovascular Risk Markers in Elderly Hypertensive Egyptian Patients
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 10
Abstract
Hypertension is a serious public health problem among elderly Egyptians. The prevalence of overweight/ obesity is also increasing in alarming proportions among the elderly, and it is correlated with the prevalence of hypertension, one of the major risk factors for cardiovascular diseases, and also strongly correlated with atherogenic dyslipidemia parameters. We aimed to determine the correlation between lipid profile, and high sensitivity C-reactive protein (hs-CRP) with anthropometric indices, as indicators of additional cardiovascular risk in a population of elderly hypertensive Egyptian patients.119 elderly hypertensive patients of both genders were enrolled in this study divided into three groups according to age. Height, weight, BMI, WC, WHR, blood pressure, lipid profile, and hs-CRP were measured for all participants. No statistical difference between the different age groups in both genders as regard height, weight, BMI, and WHR. WC tends to decrease significantly with age in both genders. A statistically significant difference was noted between different age groups only in women as regards; total cholesterol (p< 0.013), and HDL-chlevels (p< 0.015). While, a statistical significant difference between was noted in both women and men regarding; LDL-ch (p< 0.016, and p< 0.021 respectively), and triglyceride (TG) levels (p< 0.011, and p< 0.032 respectively).Both SBP, and DBP tend to increase with age, with no statistical significant difference was noted between the different age groups in both genders. (p<0.136 and p<0.0.365 in women, p<0.251, and p<0.152 in men).hs-CRP values tend to increase progressively with age with, a statistical significant difference between the three studied groups in both genders. (p<0.036, and p<0.013 respectively). In group I, BMI, WC, and WHR all were correlated with lipid profile and blood pressure, while, in group II, BMI and WC, but not WHR were correlated with lipid profile and blood pressure, and in group III, none of these indices were correlated with lipid profile or blood pressure. In all studied age groups; total cholesterol, LDL-ch, and triglycerides were positively correlated, and HDL-ch was negatively correlated with systolic and diastolic blood pressure. Total cholesterol, LDL-ch, and triglycerides were positively correlated, and HDL-ch was negatively correlated with hs-CRP. Both systolic and diastolic blood pressures were positively correlated with hs-CRP. We concluded that anthropometric indices are strongly correlated with hypertension, one of the major risk factors for cardiovascular diseases, and also strongly correlated with atherogenic dyslipidemia parameters. Assessing the hs-CRP levels may thus provide additive value in predicting cardiovascular risks
Authors and Affiliations
Marwa A. Saad M. D
Keywords
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