Study to Assess C Reactive Protein as a Biochemical Severity Marker for Acute Pancreatitis
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 1
Abstract
Majority of Acute pancreatitis are due to gall stone induced(1) and alcohol induced (2). Various theories have been proposed for the mechanism involved in pancreatitis like Bile reflux (3) from CBD to main pancreatic duct, Duodenal reflux theory (4), Ductal hypertension theory (5) and so on. Acinar cells are affected first. But the mechanism of injury by alcohol and drugs is not known. Calcium activates and can increase the activation of other intra cellular enzymes (6). Pancreatic enzyme activation within acinar cells is seen in all models of pancreatitis. It is being held that intra acinar activation of enzymes is the critical event in pancreatitis leading to injury of acinar cells (7). These changes produce significant inflammatory reaction in and around the pancreas.
Authors and Affiliations
Prof. Dr. Kulandaivelu Shanthakumar
Keywords
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