STUDYING THE THE EFFECT OF GAMMA (γ)–RADIATION ON AMYLOLYTIC ACTIVENESS IN THE BLOOD AND HOMOGENATE OF RATS AT DIFFERENT PHYSIOLOGICAL AGE STAGE
Journal Title: ASIAN JOURNAL OF NATURAL & APPLIED SCIENCES - Year 2019, Vol 8, Issue 1
Abstract
The aim of the research lies on studying the the effect of gamma (γ)–radiation on amylolytic activeness in the blood and homogenate of young (2 months old), mature (6 months old) and old (36 months old) rats at different physiological age stages. In the experiments, the effect of γ–radiation (4 Gr) was carried out on the rats by means of radiation device "Luch" (Latvia) based on the 60Co radioactive isotope. In the experiments, it was found that amilolytic activity in blood of young rats was decreased by ~20% in comparison with the control group within 20 days by the effect of γ–radiation, and its restoration in blood and liver homogenate until the value of control group on the 60–day. It was identified that as the result of γ–radiation the effectiveness of amylolytic activity in the blood of mature rats decreased by 58±0.3% in comparison with the control group on the 20–day, it approximated to the control group value on the 60–day, and amilolytic activity in liver homogenate was lower than that of the control group even on the 60–day after γ–radiation. It was found out that amylolytic activity in the blood of old rats reduced by ~20% in comparison with the control group on the 20–day after γ–radiation, it approximated to the control group on the 30–day, amylolytic activity in liver homogenate decreased in compariron with the control group after γ–radiation and it did not regenerate even on the 60–day. The results obtained can be explained by the significant difference in experimental animals' different digestive system enzyme secretion/incretion mechanisms at different age stage, as well as significant difference of their compensatory/adaptive mechanisms of responses to the effect of γ–radiation.
Authors and Affiliations
Dumaeva N. Zukhrakhon, Kadirov K. Shokir
Keywords
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