Successful Thrombolysis of Aortic Prosthetic Valve Thrombosis during First Trimester of Pregnancy

Apply

Successful Thrombolysis of Aortic Prosthetic Valve Thrombosis during First Trimester of Pregnancy 

Journal Title: Internet Journal of Medical Update - Year 2015, Vol 10, Issue 1

Abstract

Prosthetic heart valve thrombosis during pregnancy is life-threatening. Standard surgical treatment using cardiopulmonary bypass carries high maternal and fetal complications. Here we report a case of an antenatal female in first trimester with aortic prosthetic valve thrombosis (PVT), who was successfully thrombolysed with streptokinase with no complication to mother or fetus. The aim was to justify the usefulness of thrombolysis as a treatment option for prosthetic valve thrombosis in antenatal patients. A 35-year-old female patient presented in the first trimester of pregnancy with PVT at aortic position. After due consent, thrombolysis was undertaken with streptokinase. During the hospital course, she was followed clinically and with echocardiography. She symptomatically improved with thrombolysis. Transthoracic echocardiography showed complete resolution of thrombus. Peak trans-aortic velocity improved from 5.5 m/s to 3.7 m/s. She delivered a normal baby uneventfully in follow up at full term of pregnancy with no complications. Fibrinolytic therapy for mechanical valve thrombosis is a reasonable alternative to surgery in first trimester of pregnancy. 

Authors and Affiliations

Anand Shukla, Abhishek Raval, Ronak Saha

Keywords

Normal plantar weight distribution pattern and its variations with change of functional position and its comparison with patients of knee osteoarthritis 

Early osteoarthritic changes at the knee result in altered plantar weight distribution pattern during stand, minisquat, squat and one leg stand positions. To study and quantify these plantar weight distribution variation...

EP ID EP95205
DOI 10.4314/ijmu.v10i1.6
Views 115
Downloads 0