“Surge of Hepatitis E infection during summer months in an urban Municipal area of West Bengal.”
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 10
Abstract
Viral hepatitis represents a major public health problem worldwide. The purpose of this observational study is to determine the epidemiologic pattern of Hepatitis E infection among patients attending a tertiary care hospital in north Kolkata and adjacent 24 Parganas, West Bengal, India. This study was performed from 1stJanuary 2015 to 31stDecember 2016 with all clinically suspected jaundice patients attending this tertiary care centre, both outpatient and inpatient clinics fulfilling the inclusion criteria. Blood was collected aseptically from clinically suspected cases, serum was separated and analysed by Immunochromatographic test to detect HEV IgM. Out of 181 cases, 46/181(25.41%) were found to be reactive. A month-wise distribution chart for 2 years i.e.; 2015 and 2016 showed 22/46 (47.82%) and 24/46 (52.17%) seropositive cases respectively. A surge of blood samples from these clinically suspected hepatitis patients were seen mainly in the summer months of April, May and June. In this study, HEV IgM reactive cases showed a seasonal variation. In 2015, out of 22 reactive cases, maximum number of cases were seen in the months of April, May and June i.e.,5/22 (22.72%), 6/22 (27.27%) and 7/22 (31.81%) respectively. In 2016, a similar surge is also seen in the summer months of April, May and June, which are 6/24 (25.00%), 7/24 (29.16%) and 9/24 (37.50%) respectively. With respect to the age distribution, highest number of reactive cases was seen between 21-30 years 20/46 (43.47%). Among all reactive cases of HEV, males 28/46 (60.86%) predominate females 18/46 (39.13%); (p<0.05). Although acute hepatitis caused by HEV is a self-limiting disease, still its rise especially during summer months, is noteworthy. Preventive measures should be taken to restrict the infection.
Authors and Affiliations
Dr. Moumita Adhikary, Dr. Partha Sarathi Chakrabarty, Dr. Sanjit Kumar Patra, Dr. Nandita Pal, Dr. Sumanta Chatterjee
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