Surgically treated early stage cervical cancer – Prognostic factors and adjuvant treatment
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2016, Vol 5, Issue 1
Abstract
Invasive cancer of cervix is considered a preventable disease as it has a long pre-invasive state. If detected in early stages i.e upto stage IIA1 the disease is curable with good survival rates. • To identify the prognostic factors in surgically treated early stage cervical cancer • To study if preoperative findings could accurately predict presence of poor prognostic factors such as nodal status • To evaluate these histological prognostic factors in deciding the further management of patient with adjuvant treatment This is a prospective study of prognostic factors and adjuvant treatment in 60 cases of surgically treated early stage cervical cancer (Radical hysterectomy with bilateral pelvic lymph node dissection).Histo-pathological findings were evaluated to determine the prognosis.Result:25% patients had lymph node involvement and lymphovascular space invasion was seen in 15% of cases. Parametrium was involved in 16.6%. There were 3 patients with positive margins and 65% patients had moderate differentiation of tumor. Maximum number of nodes were positive in stage IB2. Size of the tumor more than 4 cm is an important determinant of prognosis and has an definite effect on lymph node metastasis and other poor histological prognostic factors. • Adjuvant treatment is must incase of patients with intermediate or high risk prognostic factors
Authors and Affiliations
Verneker Ruchika A| Consultant gynaecologist Madhuram Hospital, Department of Gynaecological oncology at Gujarat cancer research institute Ahmedabad, Correspondence Email : ruchika2103@gmail.com, Desai Arun J| Consultant gynaecologist Shivam Hospital , Department of Gynaecological oncology at Gujarat cancer research institute Ahmedabad, Patel Shilpa M. | Department of Gynaecological oncology at Gujarat cancer research institute Ahmedabad
Keywords
Related Articles
- EP ID EP11541
- DOI -
- Views 250
- Downloads 8
Pharmacoeconomic Evaluation, Cost Minimization Analysis of Anti-Diabetic Therapy in Gujarat
Economic burden of DM was approximated $ 132 billion in 2002. 55 patients with DM were recruited. Their clinical information was analyzed for most commonly and most costly prescribed drug molecule. Three brands of both...
Pilomatrixoma in the Parotid Region - A Case Report
Pilomatrixoma is a relatively benign cutaneous adnexal neoplasm with differentiation towards the matrix and inner sheath of a normal hair follicle as well as hair cortex. It is commonly seen in head and neck region. We...
ASSESSMENT OF PROLIFERATIVE POTENTIAL OF TUMOR CELLS USING KI-67 EXPRESSION AND MORPHOMETRICAL ANALYSIS FOR PROGNOSTICATION OF ORAL SQUAMOUS CELL CARCINOMAS
Background: Cancer cells exhibit a characteristic intrinsic ability of uncontrolled cell proliferation which plays a vital role in tumor development and progression. The Ki-67 antigen expression is strictly associated...
The Effectiveness of Transcranial Direct Current Stimulation (tDCS) on Reducing Depression Severity and Automatic Thoughts in Depressed Women
Introduction: Depression is a common disorder that is ofen associated with other mental and physical disorders. One of the innovative approaches applied in depressed patients is transcranial direct current stimulation....
A comparative study of Epstein-Barr virus (EBV) in malignant tumors and fibrocystic lesions of the breast
Breast cancer is the most common non-skin malignancy and the second leading cause of death due to cancer in women (after lung cancer). Several factors involved in this disease have been studied. EBV has been proposed as...