Survival in Advanced Esophageal Cancer – Experience from a Tertiary Cancer Center
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 2
Abstract
Introduction: Esophageal cancer is the eighth most common malignancy worldwide. In the Western world, esophageal adenocarcinoma has surpassed the incidence of squamous cell carcinoma (SCC). However in developing countries, SCC is still the most common type of esophageal cancer with adenocarcinoma being relatively less common. In this study a retrospective analysis of demographic data and survival in locally advanced carcinoma esophagus treated with chemoradiation (CRT) at our institute was done. Material and Methods: A total of 83 patients with the pathological diagnosis of carcinoma esophagus treated at our institute from January 2008 to December 2013 were retrospectively analyzed from treatment and follow up records. Statistical analysis was done by using SPSS 20 software. Results: The median age was 56 years, with male:female ratio of 1.6:1. SCC was the most common histology (87%). Lower thoracic was the most common tumor location followed by middle and upper third. Follow up data was available for 47 patients. Among them 35 patients received treatment with curative intent with CRT and the median overall survival was 22 months. Conclusion: SCC was the predominant histology. Most of the patients sent for CRT were in an advanced stage. Survival was similar to other published data.
Authors and Affiliations
Deepa Joseph, Monica Malik Irukulla, Syed Fayaz Ahmed, Deepthi Valiyaveettil
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