Sustainability and Clinical Effectiveness of Inpatient Rehabilitation in Painful Shoulder Diseases
Journal Title: Journal of Rheumatic Diseases and Treatment - Year 2017, Vol 3, Issue 3
Abstract
Objective Complaints of the shoulder are often accompanied with pain, function lease and impaired quality of life. Inpatient rehabilitation in Austria acts as a powerful non-operative intervention to improve shoulder function and to reduce pain. The aim of this presented study was to observe the long-lasting effects of rehabilitation on shoulder complaints in a follow up trial. Design The impact of three-week inpatient rehabilitation on pain, sleep quality and shoulder function, respectively biomarkers for stress and pain was investigated in a multicenter study. Patients 150 inpatient rehabilitation patients with painful shoulder disorders were recruited to a follow up study (baseline, three weeks, three months, and six months). Methods Data were collected by standardized questionnaires concerning function and sleep quality. Pain intensity was determined by Visual Analogue Scale (VAS). Additional biomarkers for stress, pain and inflammation (CRP, Serotonin, ACTH, Dynorphin, ß-Endorphin) were analyzed by ELISA technique or HPLC. Results Many investigated parameters, mainly pain (VAS) and function (Quick Dash/Constant Murley score) improved significantly during and after the rehabilitation program. Fewer effects could be seen in the biomarkers in serum. Furthermore, the reduction of pain was not gender dependent. Conclusion The improvement of our main outcome parameters showed that an inpatient rehabilitation program has a long-lasting effect on pain and function in shoulder disabilities and is therefore very important for the improvement in quality of life.
Glucocorticoid-Induced Leucine Zipper (Gilz) in Rheumatoid Arthritis: Relationship with Disease Activity and Steroid Use
Aims: Approximately 50% of rheumatoid arthritis (RA) patients require treatment with glucocorticoids (GC) to control inflammation [1]. Although effective, GC cause numerous adverse effects. Glucocorticoid-induced leucine...
Impact of the Addition of Ginger Extract and Copper Sulphate to Glucosamine Sulphate on Il-1β-Stimulated Chondrocytes
Introduction: Oxidative stress is an important component of the pathogenesis of osteoarthritis. NADPH oxidase Nox4 is a reactive oxygen species (ROS) producing enzyme highly expressed in chondrocytes and may be a key con...
Relationship between Serum 25-Hydroxyvitamin D Levels, Disease Activity and Anti-Cyclic Citrullinated Peptide Antibody Levels in Indian Rheumatoid Arthritis Patients
Objectives To evaluate the 25-OH vitamin D status in Rheumatoid Arthritis (RA) patients and to assess the relationship between serum 25-OH vitamin D levels with disease activity and anti-cyclic citrullinated peptide anti...
Relapsing Polychondritis with Central Nervous System Involvement Presented as Encephalitis: 7 Cases and Literature Review
Objectives: This study aims to describe the clinical manifests, CSF features and brain MRI characters of patients with relapsing polychondritis (RP) and central nervous system (CNS) involvement presented as encephalitis....
HLA-DR Frequency in Individuals with Rheumatoid Arthritis and Lung Affection
Objective: Establishing the frequency of HLA-DR antigens in a group of individuals with rheumatoid arthritis (RA) and investigate the correlation of such antigens with pulmonary involvement. Participants and methods: Th...