SWIMMING EXERCISE STIMULATES NEURO-GENESIS IN THE SUBVENTRICULAR ZONE VIA INCREASE IN SYNAPSIN I AND NERVE GROWTH FACTOR LEVELS
Journal Title: Biology of Sport - Year 2014, Vol 31, Issue 4
Abstract
In this study, we investigated the effects of 8-weeks of swimming exercise on neurogenesis in the subventricular zone (SVZ) and on the levels of nerve growth factor (NGF) and synapsin I protein in the olfactory bulb (OB) of adult rats at a series of relevant time points (2 days, 1 week, 2 weeks, 4 weeks, 3 months, and 6 months). Ninety-six male Sprague Dawley rats were divided into 2 groups: (1) a control group (COG; n = 48, n = 8 for each time point) and (2) a swimming exercise group (SEG; total n = 48; n = 8 for each time point). SEG performed swimming exercise for 5 days per week over a period of 8 weeks. We found that the number of 5-bromo-2’-deoxyuridine-5’-monophosphate (BrdU)- and doublecortin (DCX)-positive cells was significantly higher in SEG than in COG at all time points (Day 2, Week 1, Week 2, Week 4, Month 3, and Month 6; p < 0.001). Furthermore, NGF and synapsin I protein levels were significantly higher in SEG on Day 2, and Weeks 1, 2, and 4 than in COG (p < 0.05 for each time point). Our findings suggest that regular swimming exercise in adult rats increases neurogenesis, neuronal survival, and neuronal maintenance in the SVZ; furthermore, swimming exercise increases the levels of NGF and synapsin I in the OB.
Authors and Affiliations
Chang-Hun Chae, Sung-Lim Jung, Sang-Hyun An, Bum-Young Park, Tae-Wan Kim, Suk-Woo Wang, Jong-Hyuck Kim, Hyo-Chul Lee, Hyun-Tae Kim
Keywords
Related Articles
- EP ID EP59217
- DOI -
- Views 104
- Downloads 0
BIAS OF JUDGING IN MEN’S ARTISTIC GYMNASTICS AT THE EUROPEAN CHAMPIONSHIP 2011
The purpose of this study was to establish the validity (unbiasedness) and reliability of E-panel judges officiating execution of exercises in men’s artistic gymnastics at the European Championship 2011 (EC 2011) in Berl...
PHYSIOLOGICAL AND LEUKOCYTE SUBSET RESPONSES TO EXERCISE AND COLD EXPOSURE IN COLD-ACCLIMATIZED SKATERS
We investigated physiological responses and changes in circulating immune cells following exercise in cold and thermoneutral conditions. Participants were short track skaters (n=9) who were acclimatized to cold condition...
EFFECTS OF BLOOD LACTATE ON OXYGEN UPTAKE KINETICS DURING RECOVERY AFTER SPRINT IN HUMANS
The purpose of this study was to examine the effects of blood lactate level (La) on oxygen uptake ( ·VO2) kinetics during recovery after short-term exercise with maximal effort (sprint). Three sprints were performed on a...
Oxygen uptake plateau occurrence in trained male and female adults
The attainment of an oxygen uptake ( ) plateau during maximal incremental exercise is often considered as a criterion for the elicitation of a maximal effort. However there is growing evidence that a ( ) plateau does not...
EFFECTS OF CYCLIC STATIC STRETCH ON FATIGUE RECOVERY OF TRICEPS SURAE IN FEMALE BASKETBALL PLAYERS
Static stretch is a safe and feasible method which usually is used before exercise to avoid muscle injury and to improve muscle performance. The purpose of this study was to determine the effects of cyclic static stretch...