Sympathetic Vascular Reactivity Has Ambiguous Relation with Age During Pregnancy
Journal Title: International Physiology - Year 2019, Vol 7, Issue 1
Abstract
Background: Pregnancy is a physiological condition associated with adaptive changes in the maternal hemodynamics and cardiovascular system. Autonomic nervous system plays a central role in this adaptation to the various needs of pregnancy. One of the well-known complication, that occurs commonly during pregnancy is pregnancy induced hypertension (PIH)/preeclampsia (PE). Impairment of autonomic functions has been suggested as one of the cause of pregnancy induced hypertension. Vascular reactivity is defined as the responsiveness of a blood vessel to a specific stimulus. Blood pressure (BP) reactivity to the cold pressor test (CPT) has been suggested as a one of the predictor of hypertension. Materials and Methods: A total of 225 pregnant females with gestation age of 7-8 weeks as per the ultra-sonographic reports were recruited in the study and were divided into 3 groups 18-23 years (n=132), 24-29 years (n= 78) and 30-35 years (n=15). Observations and Results: The baseline SBP were 102.90 ± 11.95 mm Hg, 103.23 ±12.58 mm Hg, and 113.23 ± 12.53 mm Hg respectively in different age groups. The baseline DBP was 63.90 ± 9.20 mm Hg, 65.78 ± 10.92 mm Hg and 71.33 ± 9.17 mm Hg. It was observed that resting SBP and DBP increased with maternal age. The change in SBP and DBP during CPT was 12.02 ± 11.56 mm Hg and 12.12 ± 10.57 mm Hg in 18-23 years of age, 13.76 ± 16.22 mm Hg and 13.15 ± 14.99 mm Hg in 24-29 years of age, 12 ± 14.62 mm Hg in 30-35 years of age. This shows that there is more change in SBP and DBP till the age of 25-29 years which further decreased in 30 -35 years of age group. Conclusion: Thus there is an ambiguous relation of sympathetic vascular reactivity with age in pregnancy
Authors and Affiliations
Reena Rani Verma
Keywords
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- EP ID EP646535
- DOI 10.21088/ip.2347.1506.7119.1
- Views 82
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