SYNTHESIS AND BIOLOGICAL STUDIES OF CHERIMOLACYCLOPEPTIDE E AND ITS N- METHYLATED ANALOG
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 12
Abstract
The N-methyl derivative of Cherimolacyclopeptide E cyclo[Phe-(Dimethyl)Tyr-Pro-Gly-Leu-Gly] was synthesized using solution phase peptide synthesis. The synthesized compound was characterized by spectral data and was evaluated for anthelmintic and insecticidal activities. The compound exhibited potent anthelmintic activity as compared to the standard drug mebendazole.
Authors and Affiliations
M Himaja , Rajan Siji , A. A Karigar, M. V Ramana
Keywords
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