SYNTHESIS AND EVALUATION OF ANTIOXIDATIVE PROPERTIES OF SUBSTITUTED 10H-PHENOTHIAZINES WITH THEIR RIBOFURANOSIDES
Journal Title: Analele Universitatii din Bucuresti. Chimie - Year 2009, Vol 18, Issue 2
Abstract
A series of novel substituted 10H-Phenothiazines were synthesized via Smiles rearrangement using specific precursors. Synthesized Phenothiazines in form of heterocyclic base were then treated with appropriate sugar to yield ribofuranosides. The compounds were evaluated for their antiradical and antioxidative properties through in vitro and in vivo studies in Swiss albino mice. The structural assignment of compounds was made on the basis of spectroscopic data and elemental analysis
Authors and Affiliations
Vibha Gautam, Meenakshi Sharma, Ravindra Samarth, Naveen Gautam, Ashok Kumar, I. Sharma, D. Gautam
Keywords
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