SYNTHESIS AND SPECTRAL CHARACTERIZATION OF SOME NEW PYRAZOLINE DERIVATIVES
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2018, Vol 7, Issue 1
Abstract
The title compounds were synthesized by condensation azachalcones with ethylacetoacetate to get intermediate 3-(pyridyl)-5-aryl-6- ethylcarboxylate-2-cyclohexenone which were subsequently treated with hydrazine hydrate to afford the title compounds 4-(pyridyl)-6- aryl-7one-5,6-dihydro-1Hindazol or pyrazoline derivatives.[1-10] The sructures of the final products were supported by spectral data (UV, IR, 1HNMR) in addition to their physical properties.
Authors and Affiliations
Abdul –Wahhab J. Al- Hamdany
Keywords
Related Articles
- EP ID EP620517
- DOI -
- Views 150
- Downloads 0
ASSESSMENT OF THE ANTIPROLIFERATIVE ACTIVITY, CELL-CYCLE ARREST, AND APOPTOTIC INDUCTION BY CAPSICUM ANNUUM ON BREAST CANCER CELLS
Breast cancer is considered one of the causes of death in worldwide. Medicinal plants and their extracted natural compounds were used for the treatment of many diseases. Herein, we investigate the cytotoxic effects of Ca...
IN VITRO EVALUATION OF THE BIOCIDAL EFFECTS OF PLANT EXTRACTS FROM KINSHASA (DR-CONGO) ON MOSQUITO LARVAE
In the course of our studies on the valorization of plants used by the Nkundo people in Democratic Republic of Congo (DRCongo), we have carried out a preliminary screening of 50 aqueous extracts (at a standard concentrat...
A REVIEW ARTICLE ON SIGNIFICANCE OF SAMSARJANA KRAMÃ AS PÃSCHÃT KARMÃ
Panchākarma is the highly preferred therapeutic modality to cure any disease with least possibility of recurrence. Panchā karma is always performed in three phases – Pūrva karma (preparatory procedures), Pradhāna karma (...
ANTIOXIDATIVE POTENTIALS OF COOKED BAMBARA GROUNDNUT BASED DIET (VIGNA SUBTERRANEAN) ON LIPID PEROXIDATION STATUS IN PRETREATED ALLOXAN INDUCED DIABETIC RATS
The present study examines the antioxidant potentials of Cooked Bambara groundnut (Vigna subterranean) based diet in pretreated alloxan induced diabetic rats. Thirty (30) male albino rats (Rattus novergicus) were ramdoml...
CHEMICAL COMPARISON STUDY OF THE VOLATILE OIL COMPONENTS IN ANISEEDS WHICH ARE SPREAD IN SYRIAN ENVIRONMENT
Aniseed volatile oil was extracted from Pimpinella Anisium L. seed collected from (Aleppo, Damascus and Homs Countrysides) fields in Syria by hexane. Aniseed volatile oil component was identified qualitatively and quanti...