Synthesis, Characterization and Antitumor Activity of Some New Oganotellurium Compounds Containing Azomethine Group, Part One

Journal Title: JOURNAL OF ADVANCES IN CHEMISTRY - Year 2014, Vol 8, Issue 1

Abstract

New tellurated schiff bases were synthesized by the reaction of the corresponding mercurated Schiff  bases compounds A1-A3 with tellurium tetrabromide in 1:1 mole ratio and  that  gave organyltellurium tribromides  A4-A6.  On the other hand, when mercurated schiff bases and tellurium tetrabromide brought  together in 2:1 mole ratio gave diorganyltellurium dibromides compounds A10-A12 followed by reduction with hydrazine hydrate gave new diorganyl tellurides A13-A15.  Reduction of compounds A4-A6 by  hydrazine hydrate gave new ditellurides A7-A9.  All compounds were characterized by elemental analysis, IR, 1H , 13C NMR, HSQC-NMR and mass spectra.  Invitro anti-tumor bioactivity of some compounds were tested. 

Authors and Affiliations

Rafid H. Al-Asadi, Tarik A. Fahad, Bahjat A. Saeed, Wasfi A. Al-Masoudi

Keywords

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  • EP ID EP652634
  • DOI 10.24297/jac.v8i1.4027
  • Views 158
  • Downloads 0

How To Cite

Rafid H. Al-Asadi, Tarik A. Fahad, Bahjat A. Saeed, Wasfi A. Al-Masoudi (2014). Synthesis, Characterization and Antitumor Activity of Some New Oganotellurium Compounds Containing Azomethine Group, Part One. JOURNAL OF ADVANCES IN CHEMISTRY, 8(1), 1464-1471. https://europub.co.uk/articles/-A-652634