Synthesis, Characterization, Antimicrobial and Antioxidant Activity of 2-Hydroxy-3-Methoxybenzaldehyde-4-Phenylthiosemicarbazone and its Pd(II) Complex, Ni(II) Mixed Ligand Complex and Cu (II) Complex having Heterocyclic Bases
Journal Title: World Journal of Pharmaceutical Sciences - Year 2017, Vol 5, Issue 12
Abstract
The New four complexes of Pd(II), [Ni(II)dppm], [Cu(II)bipyridyl] and [Cu(II)phenanthroline] were synthesized with 2-hydroxy-3-methoxybenzaldehyde-4-phenylthiosemicarbazone HMBPTSC (L). The FT-IR spectral data indicated the coordination of sulphur and azomethine nitrogen atoms with the central metal ion. The EPR spectra of absorptions were observed for complexes Cu (II) bipy the g values as g┴ = 2.070, g‖‖ = 2.348 and Cu(II)phen g┴ = 2.0705, g‖‖ = 2.364 respectively. The g values are found in both the complexes had suggested elongated tetragonal geometry. The ligand and its complexes were evaluated for their antibacterial, antifungal activity, that [Ni(II)dppm-L] shows excellent activity. All the compounds showed good antioxidant activities.
Authors and Affiliations
Varada Reddy A
Keywords
Related Articles
- EP ID EP331184
- DOI -
- Views 87
- Downloads 0
Correlation of the structural changes in OCT with functional visual field defects among Primary Open angle Glaucoma patients
Glaucoma is characterized by progressive degeneration of retinal ganglion cells and their axons that leads to nerve fiber layer loss, optic disc cupping, and consecutive glaucomatous visual field changes. Study is done i...
Recombinant DNA technology in drug discovery
Recombinant DNA (rDNA) technology has made a revolutionary impact in the area of human healthcare by enabling mass production of safe, pure and effective rDNA expression products. Constructing a recombinant DNA molecule...
Herb Preparations Improve the Viability of Hippocampal Cells Suppressed by Amyloid Beta (1-42) Peptide
The aggregated amyloid peptides (Aβs) are considered as the hallmarks of Alzheimer's disease. We studied the ability of plant preparations, decreasing the aggregation state of amyloid peptides, to improve the viability o...
Assessment of knowledge, awareness and reporting of pharmacovigilance among the healthcare providers in a tertiary care center
There is a considerable increase in awareness about the issues related to drug safety among health care providers, healthcare institutions and the public. Our aim of this present study was to assess the knowledge; awaren...
A study to assess the oral health status and treatment needs of fishermen population in coastal region of Andhra
The study was conducted in Vodarevu coastal village of Prakasam district of Andhra was selected by multistage sampling method. All the available 158 fishermen were examined with their consent. The oral health status was...