Synthesis, Characterization, Antimicrobial and Antioxidant Activity of 2-Hydroxy-3-Methoxybenzaldehyde-4-Phenylthiosemicarbazone and its Pd(II) Complex, Ni(II) Mixed Ligand Complex and Cu (II) Complex having Heterocyclic Bases
Journal Title: World Journal of Pharmaceutical Sciences - Year 2017, Vol 5, Issue 12
Abstract
The New four complexes of Pd(II), [Ni(II)dppm], [Cu(II)bipyridyl] and [Cu(II)phenanthroline] were synthesized with 2-hydroxy-3-methoxybenzaldehyde-4-phenylthiosemicarbazone HMBPTSC (L). The FT-IR spectral data indicated the coordination of sulphur and azomethine nitrogen atoms with the central metal ion. The EPR spectra of absorptions were observed for complexes Cu (II) bipy the g values as g┴ = 2.070, g‖‖ = 2.348 and Cu(II)phen g┴ = 2.0705, g‖‖ = 2.364 respectively. The g values are found in both the complexes had suggested elongated tetragonal geometry. The ligand and its complexes were evaluated for their antibacterial, antifungal activity, that [Ni(II)dppm-L] shows excellent activity. All the compounds showed good antioxidant activities.
Authors and Affiliations
Varada Reddy A
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