SYNTHESIS, CHARECTERISATION AND BIOLOGICAL EVALUATION OF A NEW SERIES OF COUMARINS
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2018, Vol 7, Issue 6
Abstract
Coumarin is a fragrant organic chemical compound in the benzopyrone chemical class, althougt it may also be seen as a synthesis sub class of lactones it is naturally found in many plants, and a colourless crystalline substance in its standard state. Present work deals with synthesis of new series of benzopyrone and their microbial activity. The synthesized compounds are characterised by using Melting point, TLC, I.R, NMR- spectroscopy, Mass spectroscopy. The synthesised compounds are evaluated for anti bacterial activity by diffused assay method, using gram negative and gram positive cultures. The compound having significant anti bacterial activity by showing zone of inhibition.
Authors and Affiliations
N. Vijaya Lakshmi
STUDY OF ACTIVE COMPOUNDS OF PLECTRANTHII AMBOINICII LEAVES GROWING IN DALAT CITY, VIETNAM AND ITS ANTIBACTERIAL AND ANTIOXIDANT ACTIVITIES
Plectranthii amboinicii (Lour.) Speng - Lamiaceae (Mexican mint) is a plant used by Vietnamese people for eating and treating some illnesses. This study is designed to quantify the oil content extraction of Folium Plectr...
EFFECT OF TELFAIRIA OCCIDENTALIS ON THE PHARMACOKINETIC PARAMETERS AND EFFICACY OF DIHYDROARTEMISININ AND AMODIAQUINE COMBINATION THERAPY
Vegetables are rich sources of bioactive compounds which often than not are capable of altering the pharmacokinetic parameters of drugs. The aim of this study was to evaluate the effect of Telfairia occidentalis on the p...
SYNTHESIS, STRUCTURAL CHARACTERIZATION AND ANTIBACTERIAL EVALUATION OF SOME NEW 2-PYRAZOLINE DERIVATIVES
The title compounds were synthesized by condensation of ethyl acetoacetate, urea and substituted benzaldehydes resulting pyrimidinones and in treating with hydrazine hydrate gave pyrimidinone hyrazides which by condensat...
IN-VITRO ANTIOXIDANT ACTIVITY AND ANTI-HYPERLIPIDEMIC EFFECT OF ETHANOL EXTRACT OF MANGIFERA INDICA LEAVES AND BARK ON WISTAR ALBINO RATS
The Anti-lipidemic activity of Mangifera indica leave and bark on rat model and in vitro antioxidant activity of the plant bark was studied. The antioxidant activity was determined using nitric oxide, 1,1-diphenyl-2-picr...
EXTRACTION, ELUCIDATION, CHARACTERIZATION AND EVALUATION OF ANTIBACTERIAL ACTIVITY OF FOUR PURE COMPOUND FROM BARRINGTONIA RACEMOSA LEAF EXTRACT
Objective: This study involves the extraction, isolation and characterization of chemical constituent from Barringtonia racemosa leaf extract. Methods: the dried leaves of Barringtonia racemosa was subjected to sequentia...