SYNTHESIS OF 2-[2-HYDROXY-5-(3-SUBSTITUTEDIMINO-1, 2, 4- DITHIAZOLO)] AMINO PHENYL INDOLES
Journal Title: Indo American Journal of Pharmaceutical Sciences - Year 2018, Vol 5, Issue 4
Abstract
2-[2-Hydroxy-5-(-2,4-substituted-dithiobiureto)]phenylindoles with iodine in ethanol as an oxidative cyclising agent was transformed into the 2-[2-hydroxy-5-(3-substitutedimino-1,2,4-dithiazolo)]aminophenylindoles in one step. Characterization and justification of structure of synthesized compounds were done on the basis of conventional elemental analysis, chemical characteristics and spectral studies. Key Words: 2-[2-Hydroxy-5-(2,4-ethyldithiobiureto)]phenylindole, iodine, ethanol.
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