Synthesis of highly pure esomeprazole sodium with polymorphic form J
Journal Title: World Journal of Pharmaceutical Sciences - Year 2016, Vol 4, Issue 11
Abstract
The present disclosure relates to a process of preparing excellent quality esomeprazole sodium, which is devoid of product related impurities. Esomeprazole sodium performed via preparation of sodium-salt using key starting material esomeprazole potassium. Herein, reported an excellent method to get polymorph J of esomeprazole sodium using acetonitrile maceration. In this development overall yield is 70-80% with purity more than 99%.
Authors and Affiliations
Dr. Sandip Sadaphal
Keywords
Related Articles
- EP ID EP203708
- DOI -
- Views 85
- Downloads 0
Management of Recurrent urinary tract infection in diabetic patient with Ayurveda and counselling- Case study
A female patient of 56 years came to the Diabetic screening and counselling OPD of Ayurveda and Unani Tibbia college & hospital in February 2015 with chief complaints of increased frequency of micturition and burning sen...
Analysis of test requisitions and optimum utilization of routine laboratory investigation in a tertiary care teaching hospital
Background: Overutilization of investigations, leads not only to excessive burden on the laboratory but also gives rise to a multitude of problems in patient management. Practice of evidence based laboratory medicine and...
Sufficient conditions in the collision avoidance problem under geometrical and integral limitations on control
The paper considers the collision avoidance problem in a system, described by a controlled equation in partial derivatives, containing the second derivative with respect to time and elliptic operator. New spaces, dependi...
Caffeine Consumption Protects Against High Fat Diet-Induced Hepatic steatosis
Nonalcoholic fatty liver disease (NAFLD) is one of the most common liver diseases and is a part of the metabolic syndrome. Currently, there are interventions that used to treat risk factors associated with NAFLD. Caffein...
Antimalarial activity of Polyalthia longifolia (False Ashoka) against chloroquine sensitive Plasmodium falciparum 3D7 strain
The present study was aimed to evaluate the antiplasmodial activity of medicinal plant Polyalthia longifolia (False Ashoka) against chloroquine (CQ)-sensitive Plasmodium falciparum 3D7 strain and cytotoxicity against THP...