Synthesis, Structure Elucidation and Biological Studies of 2-{[5-(4-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-arylacetamide derivatives
Journal Title: Journal of Biological and chemical Chronicles - Year 2018, Vol 4, Issue 1
Abstract
A series of ten derivatives of titled compounds was designed and synthesized using appropriate route and structures of compounds were determined by FT-IR, 1H NMR and Mass spectroscopy analysis. The synthesized compounds were evaluated for their invitro antibacterial potential using bacterial strain Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa and Escherichia coli where some of the compounds showed their activeness against the strain.
Authors and Affiliations
J. P. Jadhav, J. B. Mahyavanshi, M. B. Shukla, K. A. Parmar
Keywords
Related Articles
- EP ID EP626043
- DOI -
- Views 194
- Downloads 0
Synthesis, Structure Elucidation and Biological Studies of 2-{[5-(4-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl]sulfanyl}-N-arylacetamide derivatives
A series of ten derivatives of titled compounds was designed and synthesized using appropriate route and structures of compounds were determined by FT-IR, 1H NMR and Mass spectroscopy analysis. The synthesized compounds...
Synthesis, Identification and Antibacterial Potency of Azo Dyes having Quinolin-8-ol and Active Methylene Moiety
In the present study we have reacted the five aryl diazonium salts prepared from nitro substituted anilines and amino substituted benzoic acids and coupled with Quinolin-8-ol and Active methylene group of pent- 1,4-dione...
Isolation and Characterisation on Proteus vulgaris from Mangrove Sediment of Vellar Estuary for Urease Production
Urease is a virulence factor found in various pathogenic bacteria. It is essential in colonization of a host organism and in maintenance of bacterial cells in tissues. Due to its enzymatic activity, urease has a toxic ef...
An Enumeration of Lichenized Fungi from Sikandra Dhar Region of District Mandi, Himachal Pradesh
Floristic studies have been initiated to explore diversity of lichenized fungi in Sikandra dhar region of district Mandi, Himachal Pradesh (India). Sikandra dhar region is situated in Shivalik hills zone of North-West Hi...
Development and Validation of New Methods for Concentration of Vegetables and Fruit Juice
Evaporation, when the juice is heated in vacuum in the appropriate trays, but this heat does not reach the boiling point, since during the boiling process all the useful substances will be destroyed. Currently, juice con...