Systemic Lupus Erythematosus: contributory factors and diagnosis.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Systemiclupus erythematosus (SLE) an autoimmune disease more common in women and those of African,Caribbean and Chinese descent. Genetic and drugs have important role in the disease. SLE has abnormalities in apoptosis (a programmed cell death).SLE is”the great imitator” it oftenmimics or is mistaken for other illnesses. Common chronic complaints include fever, malaise, jointpain, muscle pain and fatigue. Neuropsychiatric syndromes can result after SLE affects CNS or peripheral nervous system. Common neuropsychiatric manifestations of SLE include cognitive dysfunction, mood disorder, cerebrovascular disease, seizure, polyneuropathy, anxiety disorder, psychosis, depression, and in some extreme cases personality disorder. Pregnancy outcome appears to be worse in people with SLE whose disease flares up during pregnancy. Thediagnostic criteria of American college of Rheumatology(ACR)is useful. Treatment includes corticosteroids and anti-malarial drugs. Intravenous immunoglobulins may be used to control SLE with organ involvement or vasculitis. No cure is available for SLE but treatments for the disease. Over 90% survive for more than 10 years
Authors and Affiliations
Murtaza Mustafa, MK. Nang, EM. Illzam, AM. Sharifa, S. Shamaila
Keywords
Related Articles
- EP ID EP432679
- DOI 10.9790/0853-1801060108.
- Views 54
- Downloads 0
Prevalence of Diastolic Dysfunction and Severity of Liver Cirrohosis
Introduction: The presence of cirrhotic cardiomyopathy, which includes a left ventricular diastolic dysfunction (DD), seems to deteriorate the course of liver cirrhosis and the prognosis. The prevalence of DD in cirrhoti...
Demographic, Clinico-Pathological Study And Management of Peptic Ulcer Perforation
Introduction: Peptic ulcer disease (PUD) is a worldwide health problem because of its high morbidity, mortality and monetary loss. The incidence of uncomplicated peptic ulcer disease has lowered dramatically due to usage...
Non Surgical Retreatment of Mandibular Second Molar – A Case Report
This case demonstrates a 3-canal mandibular second molar treated by non-surgical root canal therapy. Acute exacerbation was noted on a previously root-filled left mandibular first molar with periapical lesions,extraoral...
The Tooth Bandaid - Restoring Esthetics
Trauma to the anterior teeth are a common sight these days, affecting children and adolescents. Coronal tooth fractures are frequently encountered. When the tooth fragment is available, reattachment of fractured tooth fr...
A Fluorescence Microscopy Study of Seminal Fluid In Infertile Males Using Acridineorange Dye To Assess DNA Integrity Along With Semen Analysis
According to World Health Organization(2000), infertility is the inability of the sexually unprotected, active couple to achieve pregnancy in one year of marriage . Present study is aimed to assess DNA damage in sperms u...