Systemic Lupus Erythematosus: contributory factors and diagnosis.
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2019, Vol 18, Issue 1
Abstract
Systemiclupus erythematosus (SLE) an autoimmune disease more common in women and those of African,Caribbean and Chinese descent. Genetic and drugs have important role in the disease. SLE has abnormalities in apoptosis (a programmed cell death).SLE is”the great imitator” it oftenmimics or is mistaken for other illnesses. Common chronic complaints include fever, malaise, jointpain, muscle pain and fatigue. Neuropsychiatric syndromes can result after SLE affects CNS or peripheral nervous system. Common neuropsychiatric manifestations of SLE include cognitive dysfunction, mood disorder, cerebrovascular disease, seizure, polyneuropathy, anxiety disorder, psychosis, depression, and in some extreme cases personality disorder. Pregnancy outcome appears to be worse in people with SLE whose disease flares up during pregnancy. Thediagnostic criteria of American college of Rheumatology(ACR)is useful. Treatment includes corticosteroids and anti-malarial drugs. Intravenous immunoglobulins may be used to control SLE with organ involvement or vasculitis. No cure is available for SLE but treatments for the disease. Over 90% survive for more than 10 years
Authors and Affiliations
Murtaza Mustafa, MK. Nang, EM. Illzam, AM. Sharifa, S. Shamaila
Keywords
Related Articles
- EP ID EP432679
- DOI 10.9790/0853-1801060108.
- Views 30
- Downloads 0
Antibiotics: A Potential Source of Pollution in the Environment
Since their discovery antibiotics have been central to modern healthcare and have been extensively and effectively used to prevent and treat infections in humans and animals. They have also been used in agriculture, aqua...
A study on etiological profile of referred otalgia
Background: Otalgia or earache is one of most commonly encountered complaint in ENT OPD. It may be due to any local ear pathology or may be due to pathology in some distant site surrounding head and neck region. The comp...
Rare Case Report of Bilateral Pigmented Lesion on Alae of Nose
Basal cell carcinoma is most common skin cancer caused by prolonged exposure to ultraviolet rays.It is also called as rodent ulcer. It primarily affects individual with light eyes,hair and fair complexion but pigmented b...
A Randomized Prospective Study To Compare Truflex Articulating Stylet Vurses Conventional Rigid Malleable Stylet As An Intubating Guide With The Macintosh Laryngoscopy During Elective Tracheal Intubation
Background: Tracheal intubation is the most common and routinely performed procedure in any surgeries requiring general anaesthesia. The current study compares the Truflex articulating stylet with the conventional rigid...
Mc Gregor Flap for Lower Eyelid Defect
Introduction: The reconstruction of a full thickness loss of the lower eyelid after neoplasm excision is an immediate functional requisite, since the eyelids are organs of primary importance for the protection of the eye...