Targeted Delivery of Curcumin to Tumors via PEG-Derivatized FTS-Based Micellar System
Journal Title: The AAPS Journal - Year 2014, Vol 16, Issue 3
Abstract
The online version of this article (doi:10.1208/s12248-014-9595-6) contains supplementary material, which is available to authorized users.
Authors and Affiliations
Yichao Chen, Xiaolan Zhang, Jianqin Lu, Yixian Huang, Jiang Li, Song Li
Comparative studies to determine the selective inhibitors for P-glycoprotein and cytochrome P 4503A4
It has been suggested that cytochrome P450 3A4 (CYP3A4) and MDR1 P-glycoprotein (P-gp) act synergistically to limit the bioavailability of orally administered agents. In order to determine the relative role of these prot...
Human membrane transporter database: A web-accessible relational database for drug transport studies and pharmacogenomics
published July 14, 2000
Structure-Based Prediction of the Nonspecific Binding of Drugs to Hepatic Microsomes
For the accurate prediction of in vivo hepatic clearance or drug–drug interaction potential through in vitro microsomal metabolic data, it is essential to evaluate the fraction unbound in hepatic microsomal incub...
Squarticles as a Lipid Nanocarrier for Delivering Diphencyprone and Minoxidil to Hair Follicles and Human Dermal Papilla Cells
Delivery of diphencyprone (DPCP) and minoxidil to hair follicles and related cells is important in the treatment of alopecia. Here we report the development of “squarticles,” nanoparticles formed from seb...
Human proton/oligopeptide transporter (POT) genes: Identification of putative human genes using bioinformatics
Purpose: The proton-dependent oligopeptide transporters (POT) gene family currently consists of ∼70 cloned cDNAs derived from diverse organisms. In mammals, two genes encoding peptide transporters, PepT1 and PepT...