Teratogenic Risk Potentiality of Blue Ternate (Clitoria ternatea) Leaf Extract Using Chorioallantoic Membrane (CAM) Assay: Phase One
Journal Title: International Journal of Current Science Research and Review - Year 2024, Vol 7, Issue 05
Abstract
The study implemented a descriptive classic experimental design within a laboratory, utilizing the Chorioallantoic Membrane (CAM) assay to investigate the teratogenic potential of Blue Ternate (Clitoria ternatea) leaf extract using the different extract concentrations, and the phytochemical analysis screening unveiled the presence of flavonoids, saponins, tannins, alkaloids, and steroids in the leaves. The primary objectives encompassed the assessment of teratogenicity at various extract concentrations, comparing results with controls, and exploring the plant’s impact on embryonic development. While no significant differences emerged in primary and secondary blood vessels among treatments, a conspicuous variation in tertiary blood vessels indicated potential teratogenic effects at specific concentrations. Nevertheless, the study concluded that Clitoria ternatea exhibits promising therapeutic attributes. Recommendations include the implementation of public awareness programs elucidating the health benefits of Blue Ternate and further investigations into refining, storage practices, and potential teratogenicity in other plant parts. These insights, of considerable value to medical practitioners and future researchers, underscore the importance of caution and consultation, especially for pregnant individuals. In summary, the research significantly contributes to understanding Blue Ternate’s safety profile, presenting avenues for future exploration. The emphasis on careful consideration in medicinal applications, particularly during pregnancy, reinforces the need for responsible and informed decision-making in healthcare practices.
Authors and Affiliations
Rheajean M. Jawel, Sylphjenn C. Orquillo, Xycris Ezenette M. Barcos, Carmel Grace B. Guazon, Arjune A. Lumayno, Nikko T. Ederio
Keywords
Related Articles
- EP ID EP735713
- DOI 10.47191/ijcsrr/V7-i5-69
- Views 51
- Downloads 0
Influence Marination Length Using Evaporated Roselle (Hibiscus sabdariffa Linn) Extract on Microbiological Quality of Beef Se'i
Experiment was conducted to determine the influence of marination length using evaporated roselle extract (Hibiscus sabdariffa Linn) on microbiological aspects of beef se’i. The completly randomized design (CRD) with 4 t...
Human Resource Needs Planning in the Technical Implementation Unit Health Laboratory Kendari City
Introduction: Human Resource Planning Is A Structured Process Used To Predict Future Workforce Needs And Availability. Analysis Of Workforce Needs Is A Logical And Planned Step In Evaluating The Number And Competency Of...
Various Analytical Methods for Analysis of Sitagliptin – A Review
Sitagliptin is a dipeptidyl- peptidase inhibitor used to treat high blood sugar levels caused by type2 diabetes. Absorption of Sitagliptin is 87% orally bioavailable and taking it with or without food does not affect its...
Voter Apathy in Nigerian Electoral Democracy: An Insidious Enigma to National Development
This paper examines voter apathy in Nigerian electoral democracy as an insidious enigma to national development, with an emphasis on the 2023 General Elections. Elections in democracies play a vital role in ensuring the...
The Role of Artificial Intelligence in Enhancing Employee Performance through SHRM and Organizational Creativity at ABC Bank Yogyakarta Area Office
This study explores the role of Artificial Intelligence (AI) in mediating the effects of Sustainability Human Resource Management (SHRM) and Organizational Creativity on employee performance. Conducted at ABC Bank’s Yogy...