The applications of MDR1 polymorphism in precision diagnosis and treatment of autoimmune disease
Journal Title: Biomedical Transformation - Year 2021, Vol 2, Issue 3
Abstract
Autoimmune disease (AID) is a disease state of self-tissue damage caused by the imbalance of immune homeostasis due to the body's response to self antigens. It is related to self antigens, abnormal immune regulation, cross antigens and genetic factors.The accurate diagnosis and treatment are a new development trend for AID clinical management. MDR1 polymorphism has shown better future applications in several areas, such as diagnosis and differential diagnosis of AID. The determination of disease activity, severity and complications. The selection for treatments in AID and prediction of therapeutic effects. MDR1 polymorphism will also contribute to personalized clinical management of AID.
Authors and Affiliations
Guo Liwei, Li Changtian
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