The assessment of thyroid autoantibody levels in euthyroid patients with polycystic ovary syndrome
Journal Title: UNKNOWN - Year 2018, Vol 19, Issue 4
Abstract
Objective: Thyroid hormone abnormalities are commonly seen in polycystic ovary syndrome (PCOS) and have considerable effects on comorbidities. The association with PCOS and thyroid autoimmunity which lead to thyroid pathologies are not revealed clearly. We targeted to commentate anti-thyroid peroxidase (anti-TPO), anti-thyroglobulin (anti-TG) antibody levels and thyroid autoimmunity in PCOS. Material and Methods: One hundred eighty four patients who got the diagnosis of PCOS regard to the revised 2003 Rotterdam criteria were embodied in this study. One hundred six age-matched female volunteers were included in the control group. Characteristics, biochemical parameters, thyroid hormone and autoantibody levels of groups were investigated. Results: Although; we did not find out a statistically significant difference in TSH and sT4 levels between two groups (p>0.05), anti-TPO and anti-TG antibody levels were determined higher in PCOS group significantly (p<0.001). Anti-TPO Ab and anti-TG Ab positivity prevalence of PCOS patients were significantly higher as against to controls (p<0.001; p=0.01). Conclusion: Not only thyroid hormone levels but also thyroid autoantibody levels should be screened during the investigation of PCOS and the patients with positive results need to be followed up carefully in the long run.
Authors and Affiliations
Sema Hepşen, Melia Karaköse, Erman Çakal, Sanem Öztekin, İlknur Ünsal, Pınar Akhanlı, Bekir Uçan, Mustafa Özbek
Keywords
Related Articles
- EP ID EP421003
- DOI 10.4274/jtgga.2018.0001
- Views 72
- Downloads 0
Detrimental effect of Hypericum perforatum on ovarian functions
Objective: Hypericum perforatum is widely used for depression and distress treatment as an over-the-counter plant at any age. This study investigated the safety of H. perforatum on ovarian function and infertility. Mater...
Are the skin scar characteristics and closure of the parietal peritoneum associated with pelvic adhesions?
Objective: To assess whether the abdominal scar characteristics and closure of the peritoneum were associated with pelvic adhesions. Materials and Methods: Patients who had undergone cesarean section between December 20...
Iodine deficiency in pregnant women at first trimester in Ankara
Objective: Iodine deficiency in pregnant woman in Ankara was shown in previous studies. We aimed to conduct a study in a tertiary center to investigate the need for iodine replacement in our population. Material and Meth...
The effect of progesterone use in the first trimester on fetal nuchal translucency
Objective: To evaluate the possible association between progesterone use in the first trimester of pregnancy and fetal nuchal translucency (NT). Material and Methods: This is an observational case-control study, which wa...
Clinical characteristics and location of lesions in patients with deep infiltrating endometriosis using the revised Enzian classification
Objective: To describe the clinical characteristics and location of lesions in patients with deeply infiltrating endometriosis using the revised Enzian (rEnzian) classification. Material and Methods: The clinical records...