The effect of progesterone use in the first trimester on fetal nuchal translucency

Journal Title: UNKNOWN - Year 2018, Vol 19, Issue 1

Abstract

Objective: To evaluate the possible association between progesterone use in the first trimester of pregnancy and fetal nuchal translucency (NT). Material and Methods: This is an observational case-control study, which was conducted with patients who underwent nuchal scans between March 2015 and February 2016 and consequently delivered live and healthy babies. The study group was composed of assisted reproductive technology pregnancies and used intravaginal progesterone 180 mg/day until gestational week 12. The control group comprised pregnant women who became pregnant spontaneously without using any progesterone preparation in the first trimester. Results: One hundred sixty-four (57.5%) of 285 patients were in the control group and 121 (42.5%) were in the progesterone group. Age, bodyweight, gravidity, and parity number of previous births and abortus, gestational week, crown-rump lengths, free β-human chorionic gonadotropin, pregnancy-associated plasma protein A, and NT values of the progesterone and control groups were recorded and we investigated whether there was a statistically significant difference between the two groups in terms of these parameters; maternal weight was found to be higher in the progesterone group than in the control group and the difference between the groups was statistically significant (p=0.019 and p=0.025). Whether the difference in NT was caused by the effect of maternal weight was investigated using the covariance analysis test and maternal weight was not found to be statistically significant in the model (p=0.284). Conclusion: Fetal NT was increased in the progesterone group compared with the untreated group in healthy pregnancies.

Authors and Affiliations

Müberra Namlı Kalem, Ziya Kalem, Batuhan Bakırarar, Ali Ergün, Timur Gürgan

Keywords

Related Articles

The effect of gender-role orientation on attitudes towards menstruation in a sample of female university students

Objective: To examine the effect of gender role orientation on attitudes towards menstruation in a sample of Iranian female students of medical sciences. Material and Methods: Three hundred female university students (94...

Detrimental effect of Hypericum perforatum on ovarian functions

Objective: Hypericum perforatum is widely used for depression and distress treatment as an over-the-counter plant at any age. This study investigated the safety of H. perforatum on ovarian function and infertility. Mater...

Assesment of pregnancy outcomes among twin pregnancies with single fetal demise regarding chorionicity and fetal death time

Objective: The objective of this study was to assess maternal and perinatal outcomes of twin pregnancies with single fetal demise in terms of chorionicity and fetal death time. Material and Methods: All deliveries betwee...

Download PDF file
  • EP ID EP365280
  • DOI 10.4274/jtgga.2017.0056
  • Views 102
  • Downloads 0

How To Cite

Müberra Namlı Kalem, Ziya Kalem, Batuhan Bakırarar, Ali Ergün, Timur Gürgan (2018). The effect of progesterone use in the first trimester on fetal nuchal translucency. UNKNOWN, 19(1), 29-33. https://europub.co.uk/articles/-A-365280