The Coexistence of Familial Mediterranean fever and Fibromyalgia Syndrome: Two Cases Reports
Journal Title: Open Journal of Orthopedics and Rheumatology - Year 2017, Vol 2, Issue 1
Abstract
Familial Mediterranean Fever (FMF) is an autoinflammatory disease caused by mutations in the MEFV gene and characterized by recurrent fever, polyserositis and arthritis. It is transmitted in an autosomal recessive pattern. FMF has been predominantly found in ethnic groups living around the Mediterranean basin (Jews, Arabs, Turks, and Armenians). Although accompanying inflammatory diseases have been reported in FMF, the coexistance of fibromyalgia syndrome (FMS) is very rare. MEFV gene analysis that the first patient had compound heterozygous mutation (M680I+V726A) and the other patient had heterozygous mutation (M694V). This association will be discussed in this case report.
Authors and Affiliations
Tural Ercan
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