The diagnosis and medical management of gastroenteropancreatic neuroendocrine tumors (GEP NET)
Journal Title: Gastroenterology Review - Year 2006, Vol 1, Issue 1
Abstract
Gastroenteropancreatic neuroendocrine tumors (GEP NET) constitute a heterogeneous group of neoplasms that are often associated with typical symptoms due to excessive and uncontrolled production of hormones and bioactive substances. The choice of treatment for GEP NET depends primarily on the pathologic differentiation and stage at diagnosis but also on the presence of symptoms related to hormonal secretion. Assessment of specific or nonspecific tumor markers offers high sensitivity in establishing the diagnosis and can also have prognostic significance. Imaging modalities include computed tomography and magnetic resonance imaging, scintigraphy with somatostatin analogs, endoscopic ultrasonography, endoscopy and substraction angiography. Surgery remains the first line therapy in NET. However these tumors are usually diagnosed at an advanced stage when cure cannot be achieved. Somatostatin analogs are important agents in the medical treatment of GEP NET. In selected cases of advanced, non-resectable disease, interferon alpha, radionuclides, ablation therapies and chemotherapy can be performed.
Authors and Affiliations
Beata Kos-Kudła, Wanda Foltyn, Anna Zemczak, Bogdan Marek, Lucyna Siemińska, Dariusz Kajdaniuk
Keywords
Related Articles
- EP ID EP112789
- DOI -
- Views 166
- Downloads 0
Does the progress in diagnosing Leśniowski-Crohn\'s disease correlate with the therapeutic procedures?
The progress in molecular analyses of genetic predisposition to Leśniowski-Crohn’s disease does not correlate with therapeutical progress. There is a constant comparison of “step-up” and “top-down” treatment, more and mo...
Kolagenowe zapalenie jelita grubego – opis przypadku
Kolagenowe zapalenie jelita grubego (KZJG) jest postacią mikroskopowego zapalenia okrężnicy, występującą kilkakrotnie częściej u kobiet niż u mężczyzn, szczególnie powyżej 50. roku życia. Manifestuje się przewlekłą wodni...
Surgical treatment of ileocaecal Leśniowski-Crohn\'s disease diagnosed during appendectomy
Treatment of the Leśniowski-Crohn’s disease is still a big challenge for many specialist doctors including surgeons. In this paper surgical treatment of the patients with Leśniowski--Crohn’s disease, localized in ileocae...
Powikłania metaboliczne choroby Leśniowskiego-Crohna
Powikłania metaboliczne choroby Leśniowskiego-Crohna stanowią następstwo złożonej patogenezy schorzenia, co prowadzi do zaburzeń wchłaniania, niedożywienia, niedoborów witamin, związków mineralnych. Szereg powikłań może...
Oswojenie wroga. Wywiad z Małgorzatą Mossakowską, prezesem Polskiego Towarzystwa Wspierania Osób z Nieswoistymi Zapaleniami Jelita J-Elita