The Diagnostic Value of Irisin and Visfatin in Experimental Testicular Torsion
Journal Title: HASEKİ TIP BÜLTENİ - Year 2017, Vol 55, Issue 4
Abstract
Aim: Testicular torsion (TT) is one of the most important causes of acute scrotum in children and young men. Very scarce number of serum laboratory parameters might be used in the early diagnosis of patients with TT. We planned this study in consideration of the possible significance of the changes in serum irisin and visfatin levels in the diagnosis of TT. Methods: We used 28 rats in four groups. In the control group, blood samples and specimens of testicular tissue were collected at 2nd and 4th hours after torsion. In the torsion groups, the left testis was twisted, and blood samples and specimens of the testicular tissue were collected at the 2nd and 4th hours for analysis. Results: There was no statistically significant difference in mean irisin and visfatin levels at the 2nd and 4th hours between rats with TT and controls. There was no statistically difference between mean irisin and vistatin levels at the 2nd hour and at the 4th hour in torsion and control groups. Conclusion: In our experimental TT method, we could not find a statistically significant difference between serum levels of irisin and visfatin. We assume that further studies are needed on this issue.
Authors and Affiliations
Fatma Saraç, Selman Yeniocak, Sevgi Büyükbeşe Sarsu, Esma Yücetaş, Vakur Olgaç, Mehmet Toptaş, Macit Koldaş
Keywords
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- EP ID EP251947
- DOI 10.4274/haseki.65375
- Views 63
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