The Diet-Heart Hypothesis: Changing Perspectives
Journal Title: Perspectives In Medical Research - Year 2018, Vol 6, Issue 2
Abstract
Introduction: The diet-heart hypothesis, i.e. dietary cholesterol and saturated fats raise the serum cholesterol which in turn is a risk factor for coronary artery disease is prevalent since the 1950s. Over the years it had a major influence on the perspectives of nutritionists, medical researchers and the lay public. However, of late, the evidence base supporting the diet-heart hypothesis is being increasingly questioned. Besides retrieval and re-analysis of archival data from incomplete studies, study of internal documents of industry reveal that vested interests may have played a role in maintaining the diet-heart hypothesis. This brief review gives an overview of the evidence and conflicting views most of which fell by the wayside in the heady days of the diet-heart hypothesis. It puts forth the question whether there is a paradigm shift in the diet-heart hypothesis. Using the key-words "diet-heart hypothesis" an online literature search was made using PubMed, Scopus and Google Scholar. Standard texts on nutritional epidemiology and other writings on the subject were reviewed.
Authors and Affiliations
Amitav Banerjee
Keywords
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