THE EFFECT OF 5 FRACTIONAL EXTRACTS OF ACER TEGMENTOSUM MAXIM. CONCENTRATED IN DECOMPRESSED VACUUM ON DENTAL CARIES-INDUCING BACTERIA
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2019, Vol 6, Issue 1
Abstract
Acer tegmentosum Maxim. (Acer TM) was concentrated in decompressed vacuum to obtain 5 factional extracts, and the amount of dental caries-inducing bacteria and periodontitis-inducing bacteria that were inhibited depending on the concentration of Acer TM was examined. The concentration of proteins contained in Acer TM Fractions 1, 2, 3, 4 and 5 was 200 (mg/mL), 225 (mg/mL), 110 (mg/mL), 150 (mg/mL) and 90 (mg/mL) respectively. The protein concentration of Acer TM Fraction 2 was the highest. The antibacterial effect of each Acer TM fraction on S. mutans was examined, and no antibacterial effect was observed in Fractions 1, 2 and 3. In the extract of Fraction 4, 2mm and 4mm antibacterial zones were observed at 50mg/ml and 100mg/ml respectively. In the extract of Fraction 5, 2mm and 4mm antibacterial zones were observed at 50mg/ml and 100mg/ml respectively. In the case of P. gingivalis, no antibacterial effect was observed in Fractions 1, 2 and 3. In Fraction 4, 1mm, 3mm, 6mm and 8mm antibacterial zones were observed at 10mg/ml, 25mg/ml, 50mg/ml and 100mg/ml respectively. In the extract of Fraction 4, an antibacterial effect was observed across the entire concentration range from the low concentration to the high concentration. In the extract of Fraction 5, 4mm and 10mm antibacterial zones were observed at 50mg/ml and 100mg/ml respectively, showing the highest antibacterial effect. Therefore, the extract of Acer TM Fractions 4 and 5 seems to be used as a candidate natural plant to treat periodontal diseases that induce dental caries-causing bacteria.
Authors and Affiliations
Kyung-Yae Hyun
CLINICAL RESPONSE OF SOFOSBUVIR (GENERIC, SEARLE) BASED TREATMENT OF CHRONIC HEPATITIS C INFECTION: A PAKISTANI REAL LIFE STUDY HOME (HEPATITIS OBSERVATIONAL MANAGEMENT ENVISION)
Background: Globally, Interferon-free direct-acting antiviral therapy has revolutionized treatment for Chronic Hepatitis C (HCV). However, due to the slow regulatory process of DAAs registration in Pakistan and differ th...
VERAPAMIL - HYDROCHLORIDE AT LOW CONCENTRATIONS INHIBITS THE GROWTH OF RELAPSE GLIOBLASTOMA
The life expectancy of glioblastoma patients was investigated in the distant postoperative period. These patients were treated with such concentrations of verapamil – hydrochloride, that minimize the level of blood cells...
ASSESSMENT OF SERUM MAGNESIUM AND CALCIUM LEVELS IN LONG STANDING TYPE 2 DIABETIC PATIENTS IN ELOBIED CITY
Introduction: Globally, diabetes mellitus is the most prevalent disease among all races and ethnicities, and hence they attach to extraordinary medical important. Mg+2 and Ca+2 are of the trace elements that have enjoyed...
EFFECT OF FIRST TRIMESTER PREGNANCY ON TRIIODOTHYRONINE, THYROXINE AND THYROID STIMULATING HORMONE AT VARIOUS AGE INTERVALS IN WOMEN OF PORT HARCOURT METROPOLIS, NIGERIA
The effect of first trimester gestation on Triiodothyronine (T3), Thyroxine (T4) and Thyroid stimulating hormone (TSH) were assessed in 90 female subjects between the ages of 18-45 years. The test subjects all in their f...
NEXUS BETWEEN HOT TEA CONSUMPTION AND RISK FOR ESOPHAGEAL CANCERS
Most of our lives revolve around our daily intake of caffeine which has increased dramatically over the years. However, China is known to be the largest consumer of caffeine around the world, especially in the form of te...