The effect of 8 weeks of Strenuous Endurance Training on Heme oxygenase-1 and TNF-α in Gastrocnemius and Soleus muscle Tissue of male Wistar rats
Journal Title: Journal of Health Research in Community - Year 2020, Vol 6, Issue 1
Abstract
Background and Objectives: Oxidative stress from exercise, either injured muscles and reduces performance in athletes, or stimulates the production of cytokines from many cells. body respond to oxidative stress by activating antioxidant defenses and other protective devices to counteract these body pressures. Therefore, the purpose of this study is to investigate the effect of 8 weeks of strenuous endurance training on HO-1 and TNF-α in gastrocnemius and soleus muscle tissue of male wistar rats. Material and Methods: 16 adult male Wistar rats, were randomly divided in 2 groups (control and endurance training). The strenuous endurance training protocol included running on the treadmill for 8 weeks (5 sessions per week). Standard meal and water were freely provided for the subjects. 24 hours after the last session of training and 4 hours of overnight fasting, tissue samples were collected and HO-1 and TNF-α levels were measured by ELISA method. Independent t-test was used for data analysis. Results: The results showed that 8 weeks of strenuous endurance training did not have a significant effect on the amount of HO-1 enzyme in gastrocnemius and soleus muscle (P˃0/05). Also, 8 weeks of strenuous endurance training had no significant effect on TNF-α in soleus and gastrocnemius muscle (P˃0/05). Discussion and conclusion: Due to the lack of effect of exercise on the levels of HO-1 and TNF-α, it can be said with caution that regular exercise has created a useful adaptation.
Authors and Affiliations
Aghaali Ghasemnian, Zahra Ghorbanlou, akram karimiasl Asl, Jabar Seifpanahi Shabani
Keywords
Related Articles
- EP ID EP701715
- DOI -
- Views 52
- Downloads 0
Epidemiological Survey of Mortality and Morbidity Caused by Cardiovascular Diseases in Patients Admitted to the Cardiac Care Units of Hamadan Educational-medical Hospitals, Hamadan, Iran, in 2017
Introduction and purpose: Cardiovascular diseases with an increasing trend are among the leading causes of death in developed countries. Therefore, epidemiological indices in mortality are recently highlighted. In this r...
Assessment of Safety Culture and the Evaluation of the Effect of Education on the Improvement of Safety in the Metal Industry during 2018
Introduction and purpose: Lack of a safety culture in organizations is the main reason for the occurrence of accidents. This phenomenon is formed in an improper safety management system and an inappropriate safety cultur...
Relationship between Social Well-being and Organizational Citizenship Behavior among Employees of Al-Zahra University Hospital, Isfahan, Iran
Introduction and purpose: Today, social health as one of the dimensions of health, along with physical and mental health, has found a widespread role and importance. The results of some studies show that social well-bein...
بررسی اپیدمیولوژی آلودگی به شپش سر و ارتباط برخی از عوامل اثرگذار بر آن در دانش آموزان مدارس ابتدایی دخترانه شهرستان تنکابن در سال 97-1396
مقدمه و هدف: آلودگی به شپش سر یکی از معضلات بهداشتی در مدارس است که منجر به ایجاد مشکلات جسمی، روحی و اجتماعی در دانش‌آموزان می‌شود. در این ارتباط، مطالعه حاضر با هدف بررسی اپیدمیولوژی آلودگی به شپش سر و ارتباط عوامل اثر...
Investigation of the Welding Workers\' Exposure to Manganese Fume in a Factory in Amol, Iran
Introduction and Purpose: Workers' exposure to manganese fumes emitted from the welding Process can lead to various ranges of diseases. This study aimed to investigate the concentration of manganese fume in the respirato...