The effect of 8 weeks of Strenuous Endurance Training on Heme oxygenase-1 and TNF-α in Gastrocnemius and Soleus muscle Tissue of male Wistar rats
Journal Title: Journal of Health Research in Community - Year 2020, Vol 6, Issue 1
Abstract
Background and Objectives: Oxidative stress from exercise, either injured muscles and reduces performance in athletes, or stimulates the production of cytokines from many cells. body respond to oxidative stress by activating antioxidant defenses and other protective devices to counteract these body pressures. Therefore, the purpose of this study is to investigate the effect of 8 weeks of strenuous endurance training on HO-1 and TNF-α in gastrocnemius and soleus muscle tissue of male wistar rats. Material and Methods: 16 adult male Wistar rats, were randomly divided in 2 groups (control and endurance training). The strenuous endurance training protocol included running on the treadmill for 8 weeks (5 sessions per week). Standard meal and water were freely provided for the subjects. 24 hours after the last session of training and 4 hours of overnight fasting, tissue samples were collected and HO-1 and TNF-α levels were measured by ELISA method. Independent t-test was used for data analysis. Results: The results showed that 8 weeks of strenuous endurance training did not have a significant effect on the amount of HO-1 enzyme in gastrocnemius and soleus muscle (P˃0/05). Also, 8 weeks of strenuous endurance training had no significant effect on TNF-α in soleus and gastrocnemius muscle (P˃0/05). Discussion and conclusion: Due to the lack of effect of exercise on the levels of HO-1 and TNF-α, it can be said with caution that regular exercise has created a useful adaptation.
Authors and Affiliations
Aghaali Ghasemnian, Zahra Ghorbanlou, akram karimiasl Asl, Jabar Seifpanahi Shabani
Keywords
Related Articles
- EP ID EP701715
- DOI -
- Views 46
- Downloads 0
An Investigation of the Relationship between Emotional Labor and Job Satisfaction among the Executives and Nursing Managers of the Teaching Hospitals Affiliated to Isfahan University of Medical Sciences
Introduction and Purpose: Due to vast and varied nature of their work, managers need to operate in a wide range of emotions. In addition, managers must be able to determine when to show certain emotions. This shows the i...
برآورد تعداد موارد مرگ ناشی از بیماری های قلبی - عروقی و تنفسی منتسب به آلاینده‌های ازن و دی اکسید نیـتروژن در هوای شهر تهران
مقدمه و هدف: امروزه یکی از مهم ترین مشکلات زیست محیطی در بسیاری از شهرهای بزرگ، وضعیت نامطلوب کیفیت هوا میباشد که سلامت ساکنین را به طور جدی به خطر می اندازد و موجب ایجاد طیف وسیعی از اثرات بهداشتی حاد و مزمن میشود. از ا...
Applications of Oregano Essential Oil (Origanum Vulgare L.) in Public Health Pests Management: A Narrative Review
Introduction and purpose: Oregano (Origanum vulgare L.) is an aromatic plant belonging to the Lamiaceae family. The aerial parts of this medicinal herb, including leaves, flowers, stems, and fruits, are used to extract e...
بررسی تأثیر برنامه آموزشی مبتنی بر مدل فرانظری بر افزایش استفاده از فرآیندهای تغییر رفتار فعالیت بدنی در کارکنان دانشگا ههای بیرجند
مقدمه و هدف: با وجود فواید زیاد فعالیت بدنی بر سلامت، هنوز بسیاری از افراد سبک زندگی بی تحرکی دارند؛ بنابراین انجام مداخلاتی به منظور ارتقاء فعالیت بدنی ضروری است. یکی از مدلهای پرکاربرد در زمینه رفتار ورزشی، مدل فرانظری...
بررسی سواد سلامت بزرگسالان 65-18 سال شهر شهریار
مقدمه و هدف: سواد سلامت یکی از اجزای مهم سلامت همگانی تلقی می گردد و به ظرفیت افراد برای کسب، پردازش و درک اطلاعات و خدمات بهداشتی مورد نیاز به منظور تصمیم گیری در زمینه های مرتبط با سلامت، سواد سلامت گفته می شود. پژوهش...