The effect of acupuncture plus drug versus drug alone on patients with mild cognitive impairment: a systematic review
Journal Title: Traditional Medicine Research - Year 2016, Vol 1, Issue 1
Abstract
Objective:The aim of this systematic review is to evaluate the effect of acupuncture plus drug versus drug alone on patients with MCI.Methods:A computerized search of the databaseswas performed from inception through February 2015. The screening of literature, the extraction of data and the assessment of methodology were independently undertaken by two reviewers. Then, a meta-analysis was performed by Review manager 5.3 version.Results:A total of 18 RCTs involving 1095 participants were incorporated into this study. Meta-analysis suggested that acupuncture plus drug for MCI could significantly improve Mini-Mental State Examination scores (MMSE) (MD1.73, 95% CI 1.28 to 2.18, random-effects model, P<0.00001, 12trials). Activities of Daily Livingscores(ADL) could be significantly improved (MD 5.63, 95%CI 4.40 to 6.87, fixed-effect model, P<0.001, 6 trials).Conclusion:With present evidences, acupuncture plus drug is more effective than drug alone for the treatment of MCI.
Authors and Affiliations
Shuai Ting, Zhang Hui, Yi Li-Juan, Tian Xu, Zeng Zi, Wang Yan, Song Guo-Min
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