The Effect of Allogenic Freeze Dried Platelet- Rich Plasma in Immunological Responses of Rabbits
Journal Title: Scholars Academic Journal of Biosciences - Year 2015, Vol 3, Issue 4
Abstract
Abstract: This study aims to analyze the effects of allogenic freeze-dried platelet-rich plasma (PRP) in immunological responses of rabbits. This study employed a design of conducting one pre-post test group to determine the effect of freeze drying on levels of TGF-β1 PRP and the post test design was only for control group conducted to determine the effect of allogenic freeze-dried PRP. Levels of TGF-β1 before and after freeze drying from nine samples of PRP were examined which were obtained from blood centrifugation of three rabbits. These nine samples were used as allogenic donor injected intramuscularly in nine rabbits for the treatment groups. The control group used nine rabbits injected intramuscularly using autologous PRP. Inflammatory response and increasing levels of IgM were observed from both groups resulted in data which were then tested statistically using independent T-test. Measurement of TGF-β1 levels before and after freeze drying were tested statistically using T- test dependent. The results showed that freeze drying process did not affect levels of TGF-β1. Allogenic freeze-dried PRP did not cause an inflammatory response in addition to not increasing levels of IgM. Keywords: autologous, allogenic, freeze dried platelet rich plasma, transforming growth factor -β1, IgM.
Authors and Affiliations
Trio Rachmawati, Sri Puji Astuti, Purwati .
Keywords
Related Articles
- EP ID EP378707
- DOI -
- Views 35
- Downloads 0
The Effectiveness of Clove Leaf Oil Antibacterial against Sub-Clinical Mastitis-Inducing Bacteria in Dairy Cattle
The effectiveness of clove leaf oil antibacterial is tested by in-vitro at Laboratory of Bacteriology, Faculty of Agriculture, University of Brawijaya, aimed to obtain the antibacterial concentration of eugenol from clov...
Sudden Hypotension during Direct Intrahepatic Porto systemic Shunt Procedure
Abstract:Extrahepatic portal vein rupture is a rare complication seen in patients undergoing direct intrahepatic portosystemic shunt procedure. Immediate recognition of this adversity helps in timely salvage of the patie...
Ethno-medicinal Study of Malayali Tribe in Jawadhuhills, Thiruvannamalai District, Tamil Nadu, South India
In the present investigation deals with the use of medicinal plants for various ailments by Malayali tribes living in Jawadhuhills, Thiruvannamalai District, Tamil Nadu, India. One hundred and eighty six Malayali tribes...
Response of Anisopteromalus calandrae (Hymenoptera: Pteromalidae) to variation in densities of its host Callosobruchus maculatus (Coleoptera: Chrysomelidae) within stored grains of Vigna subterranea (L.) Verdc (Fabaceae)
Bambara groundnut [Vigna subterranea (L.) Verdc (Fabaceae)] is an important source of protein for rural populations in sub-Saharan Africa. During storage, this commodity is destroyed by Callosobruchus maculatus (Coleopte...
Oral Stereognosis in Edentulous patients in South Indian Population
The ability to predict patient's performance with complete dentures remains elusive, irrespective of the method and the level of clinical proficiency employed in the fabrication of the prosthesis as some patients with cl...