The Effect of Astaxanthin and Regular Training on Dynamic Pattern of Oxidative Stress on Male under Strenuous Exercise
Journal Title: Indonesian Journal of Clinical Pharmacy - Year 2017, Vol 6, Issue 1
Abstract
Strenuous physical activity will induce higher Reactive Oxygen Species (ROS) level in human body that can be measured by serum malondialdehyde (MDA) level. Malondialdehyde is product of lipid peroxidation process that defined as oxidative damage of lipid biomolecule by reactivity of reactive oxygen species. Still, the dynamic pattern of malondialdehyde (MDA) level under strenuous exercise is not fully understood. Potent antioxidant such as astaxanthin and training may altered the level of MDA. Thus, the purpose of this study is to understand the effect of astaxanthin to MDA dynamic pattern on training male after strenuous physical activity. It was a double blind, experimental study, conducted on thirty young male age, divided into untrained and trained groups. Supplement astaxanthin was given to 15 subject as well as plasebo for one week. After supplementation, subjects were tested with anaerobic strenuous physical activity. The values were analyzed with ANOVA test followed by Duncan test showed that in every group, mean of MDA before test was similar, started increasing significantly after test, began decreasing at 6th hour post test and back to baseline at 24th hour post test (p<0.05), except for group of untrained male with plasebo, the value still increase twice from baseline. The lowest mean of MDA was found on group of trained male with astaxanthin supplementation and the highest was found on group of untrained male with placebo (p<0.05). These findings support that astaxanthin and training might have positive effect to oxidative stress condition without altered its dynamic pattern in male after strenuous physical activity.
Authors and Affiliations
Nova Sylviana, Hanna Gunawan, Ronny Lesmana, Ambrosius Purba, Ieva B. Akbar
Keywords
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- EP ID EP369595
- DOI 10.15416/ijcp.2017.6.1.46
- Views 75
- Downloads 0
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