The effect of insertion/deletion polymorphisms within the promoter and intron 1 sequences of the PRNP gene on the breeding value of Holstein-Friesian bulls
Journal Title: Animal Science Papers and Reports - Year 2015, Vol 33, Issue 1
Abstract
The aim of this study was to verify the hypothesis that insertion/deletion (indel) polymorphisms within the promoter and intron 1 sequences of the prion protein (PRNP) gene can affect the breeding value of Holstein-Friesian bulls. The experimental material included 261 Holstein-Friesian bulls born between 1997 – 2002. It was shown that the polymorphism in the intron 1 (12 bp indel) sequence had a more significant effect on the analyzed traits than a polymorphism in the promoter (23 bp indel) sequence. A deletion allele within intron 1 (12del) significantly increased the bulls’ breeding value for milk yield (p=0.001), protein yield (p=0.042), type and conformation (p=0.018), udder width (p=0.003), dairy character (p=0.004), and decreased days open (p=0.022). A deletion allele (23del) at the polymorphic locus of the promoter significantly decreased the bulls’ breeding value for milk yield (p=0.001), udder width (p=0.029) and dairy character (p=0.033). Analysis of both alleles showed that 23del-12del haplotype increased the bulls’ breeding value for udder traits: udder (p=0.008), fore udder (p=0.043) and udder depth (p=0.041), and decreased for fat content (p=0.047) and conformation traits - body depth (p<0.001), chest width (p=0.029) and rear leg set - side view (p=0.029). Also positive effect of 23del-12ins haplotype for days open (p=0.003) and days between calving and first insemination (p=0.045) was observed.
Authors and Affiliations
Urszula Czarnik, Janusz Strychalski, Kamil Oleński, Marta Barcewicz, Dorota Maria Hering, Paulina Puckowska, Mariusz Pierzchała, Paweł Urbański, Chandra Shekhar Pareek
Keywords
Related Articles
- EP ID EP70301
- DOI -
- Views 152
- Downloads 0
The effect of feeding linseed cake on milk yield and milk fatty acid profile in goats
The study aimed at determining the effect of supplementation the diet with linseed on milk yield and milk fatty acids profile in the middle stage of lactation of goats. Used were 16 Polish Fawn Improved goats divided int...
Genetic relationships among calving ease, birth weight and perinatal calf survival in Charolais cattle
Perinatal calf mortality affects profitability of beef cattle production systems, hence, it would eventually be beneficial to include this trait in a breeding goal. The objectives of this study were to estimate the envir...
Influence of combined supplementation of cows’ diet with linseed and fish oil on the thrombogenic and atherogenic indicators of milk fat
The study was conducted on Polish Holstein Black-and-White cows. From a herd of about 300 animals maintained in a free-stall dairy shed, two groups of 10 were selected by the analogue method: primiparous (P) and second-l...
Haematological indices, size of erythrocytes and haemoglobin saturation in broiler chickens kept in commercial conditions
The study aimed at analysing and comparing haematological indices, blood saturation and dimensions of red blood cells of Ross 308 broiler chickens of both sexes. On day 44 of rearing, blood was withdrawn once from 60 ran...
Glucose infusion response to some biochemical parameters in dairy cows during the transition period
The aim of this study was to evaluate the effect of pre-partum versus post-partum periods on the biochemical profile in dairy cows. The effect of glucose tolerance test (GTT) on glucose (Gluon-farm) and β-Hydroxybutyrate...