THE EFFECT OF OMEGA® ROOTS + GINSENG ALOE VERA, A NIGERIAN HERBAL MIXTURE, ON HAEMATOLOGICAL PARAMETERS OF NORMAL EXPERIMENTAL RATS
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2018, Vol 8, Issue 3
Abstract
Omega® Roots + Ginseng Aloe Vera herbal mixture is a commonly sold herbal formulation used for treatment of ailments. The aim of this study is to evaluate the toxic effect of Omega® Roots herbal mixture on the haematological parameters of Wistar rats. Twenty rats were used for this study and were divided into four groups of 5 animals each; the control group was administered normal saline 10 ml/kg, and the treated groups received 250 mg/kg, 500 mg/kg, and 1000 mg/kg of the herbal mixture (Omega® Roots) a period of fourteen days after which blood samples were collected for haematological analysis. The results of this study showed that oral administration of the Omega® Roots extract had a non-significantly (P˃0.05) change in the red blood cell count, white blood cell count, packed cell volume, and hemoglobin concentration of the Wistar rats. The findings suggest that Omega® Roots + Ginseng Aloe Vera herbal mixture is non-haematotoxic following acute administration.
BENEFIT OF TOPIRAMATE IN THE TREATMENT OF SYMPTOMS OF BORDERLINE PERSONALITY DISORDER: A TYPICAL REVIEW
Topiramate is a new antiepileptic drug (AED) that has been approved worldwide (in more than 80 countries) for the treatment of various kinds of epilepsy. It is currently being evaluated for its effect in various neurolog...
IN-VITRO RELEASE STUDY AND ANTIMICROBIAL PROPERTY EVALUATION OF OFLOXACIN LOADED POLY (2-HYDROXYETHYL METHACRYLATE) / POLY (CAPROLACTONE) / POLY (ETHYLENE GLYCOL) HYDROGEL SYSTEM FOR BURN WOUND MANAGEMENT
Monomer 2-hydroxy ethyl methacrylate containing small amounts of poly(caprolactone) and poly(ethylene glycol) incorporated with an antibiotic ofloxacin was polymerized by photopolymerization technique using 2,4,6 trimeth...
FORMULATION AND OPTIMIZATION OF FAST DISSOLVING TABLETS OF PROMETHAZINE THEOCLATE USING 32 FACTORIAL DESIGN
The fast dissolving tablets of Promethazine Theoclate were prepared by sublimation technique, using 32 full factorial design. This research work aimed to study and to develop a unique drug delivery system for immediate r...
EXPLORATION OF ANTI-HYPERGLYCEMIC AND HYPOLIPIDEMIC ACTIVITIES OF ETHANOLIC EXTRACT OF TINOSPORA CARDIFOLIA (WILD)HOOK WHOLE PLANT IN ALLOXAN INDUCED DIABETIC RATS
Natural remedies from medicinal plants are considered to be effective and safe alternative treatment for diabetes mellitus. The aim of present study was to demonstrate the hypoglycemic and anti-diabetic activity of the E...
ASSESSMENT OF ANTIDIABETIC POTENCIAL OF LEUCAS CEPHALOTES SPRENG EXTRACT IN ALLOXAN INDUCED LABORATORY ANIMALS
The objective of this study is to investigate the alcoholic extract of Leucas cephalotes for antidiabetic effects in laboratory animals. Diabetes was induced in rats by administration of alloxan (120 mg/kg body wt.). In...