The effect of packed red blood cell transfusion on arterial blood gas parameters in patients undergoing general anesthesia for elective surgery
Journal Title: Khoon - Year 2006, Vol 3, Issue 2
Abstract
Abstract Background and Objectives Transfusion of blood products is associated with a number of changes in metabolic parameters. The aim of this study was to assess the effects of transfusing packed red blood cells on arterial blood gas parameters in the patients undergoing general anesthesia for elective surgery. Materials and Methods In a clinical trial, each one of the 40 adult cases undergoing general anesthesia for elective surgeries received a unit of packed cell with a volume of 250 to 350 ml. The arterial samples were taken from these recipients exactly both before and after the transfusion. P value less than 0.05 was considered significant; data entry and analysis were done using SPSS software version 11.5. The results were demonstrated as mean ± standard deviation. Chi square and paired sample T tests were used for data analysis. Results There was no statistically significant difference between the two samples regarding arterial values of pH, Base Excess, PaO2, and PaCO2 before and after transfusion of one unit of packed red cell. There was, however, a significant decline in the arterial amount of bicarbonate and Buffer Base after the transfusion. Conclusions Packed cell transfusion as much as one unit or so in those patients undergoing general anesthesia could not influence the blood gas parameters in such a notable way. However, it seems that there is no reason to administer any routine dose of intravenous bicarbonate after such a transfusion, unless indicated otherwise by arterial blood gas documentation. Key words: General anesthesia, Blood transfusion, ABG, Packed red blood cell SJIBTO 2006; 3(2): 111-119 Received: 22 Feb 2006 Accepted: 2 May 2006 Correspondence: Dabbagh A.(MD). Assistant professor of Anesthesiology. Shahid Beheshti University of Medical Sciences P.O.Box: 75135, Tehran, Iran. Tel: (09821) 44458648; Fax : (09821) 22403694 E-mail: alidabbagh@yahoo.com
Authors and Affiliations
Ali Dabbagh, Mahvash Agah , Morteza Golchin, Bahman Malek
Keywords
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