The effect of single dose of preoperative dexamethasone on postoperative nausea and vomiting after laparoscopic cholecystectomy: a randomized, double-blind, placebo-controlled study
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 6
Abstract
Objective: To study the efficacy of single dose of preoperative dexamethasone in the prevention of postoperative nausea and vomiting in patients undergoing laparoscopic cholecystectomy. Materials and Methods: 110 patients were randomized in two equal groups. Each of the groups received either 2ml (8mg) intravenous dexamethasone (Group A) or 2ml intravenous normal saline as placebo (Group B). Results: 6 patients (14.5%) in group A and 19 patients (34.5%) in group B had postoperative nausea and vomiting in first 6 hours whereas 2 patients (3.6%) in group A and 5 patients (9.0%) in group B had postoperative nausea and vomiting in 6-24 hours. Conclusion: Preoperative dexamethasone improves the surgical outcome by reducing disabling symptoms of nausea and vomiting without apparent side-effects. So we suggest that single dose of preoperative dexamethasone should be used as a routine in patients undergoing elective laparoscopic cholecystectomy
Authors and Affiliations
C. P Pandey
Keywords
Related Articles
- EP ID EP512649
- DOI -
- Views 67
- Downloads 0
A Comparative Study of Biliary and Serum Lipid Profiles in Patients of Obstructive jaundice due to stones in common bile duct
The prevalence of cholesterol gallstones and common bile duct (CBD) stones in India is very high depending on dietary patterns and ethnic background. It is now widely accepted that the primary event in the pathogenesis o...
Reversible Night Blindness in an Adult – A Case Report
Vitamin A deficiency is rare in adults, still rarer is the fundus changes due to it. We report a case of 55 years old male with post gastric bypass surgery status, presenting with defective distant vision for 2 years who...
Period Prevalence of Bronchiectasis in Moderate and Severe COPD
Chronic obstructive pulmonary disease (COPD), a common preventable and treatable disease characterised by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory res...
Post-Partum Hemorrhage- What is the Vital Back up in a Government Tertiary Care Institution
Severe Obstetric hemorrhage is the most dreaded obstetric emergency. The most common type of obstetric hemorrhage is post-partum hemorrhage (PPH). PPH remains a foremost cause of maternal mortality and morbidity worldwid...
Rhinosporidiosis of Penile Shaft: A Rare Case Report
Rhinosporidiosis is a chronic granulomatous disease caused by Rhinosporidium seeberi (earlier described as a fungus, now reclassified in its own class Mesomycetozoea). India and Sri Lanka are the endemic regions for rhin...