THE EFFECT OF SOME BIOCHEMICAL PARAMETERS AND SOME MINERAL SUBSTANCES IN RATS WITH DIFFERENT DOSES OF ELLAGIC ACID
Journal Title: WORLD JOURNAL PHARMACY AND PHARMACEUTICAL SCIENCE - Year 2019, Vol 8, Issue 1
Abstract
Background: The present study was conducted for the purpose of determining the dose of Ellagic Acid with which it may show its effects on some biochemical parameters and in some mineral substances. Materials and Methods: For this purpose, 40 male rats (Wistar-albino) that weighted 200-250 g were used in the study. A total of 5 groups of rats were formed and there were 8 rats in each group; the Control Group, Group 1 (EA 3 mg/kg), Group 2 (EA 10 mg/kg), Group 3 (EA 12 mg/kg), and Group 4 (EA 20 mg/kg). After 8 weeks of oral Ellagic Acid (EA) administration every other day, the measurements of the biochemical parameters in blood samples were made with a modular auto-analyzer device by using a commercial kit. Results: When the mineral substance levels were compared with the Control Group, it was determined that the Glukoz, T.bil., İ.bil., albumin, Mg, Cl, UIBC levels increased in all groups to which EA was administered, and the Ca, Fe, urea, BUN levels decreased. Conclusion: As a result, based on the data obtained in the present study, it may be claimed that Ellagic Acid decreases the absorption of some mineral substances.
Authors and Affiliations
Dr. Leyla Mis
Keywords
Related Articles
- EP ID EP666820
- DOI -
- Views 100
- Downloads 0
A MINI REVIEW ON AROMA THERAPY
Nowadays, use of alternative and complementary therapies with main stream medicine has gained the momentum. Aroma therapies are one of the complimentary therapies which use essential oils as the major therapeutic agents...
COMPARATIVE HPLC STUDY OF RELEASE KINETICS OF THE COCRYSTALLIZED AS WELL AS MIXTURE OF ACTIVE PHARMACEUTICAL INGREDIENTS OF ASPIRIN, IBUPROFEN, INDOMETHACIN, DICLOFENAC SODIUM AND PARACETAMOL IN BODY FLUIDS
Aspirin, Ibuprofen, Indomethacin, Diclofenac sodium and Paracetamol are taken as NSAIDs. All drugs have free carboxylic acid group (–COOH) and paracetamol has free phenolic group (–OH) so all are acidic in nature. The co...
COMPARE THE EFFECTS OF DEEP NECK FLEXOR STRENGTHENING EXERCISES VERSES ELECTROTHERAPY MODALITIES ON HEAD FORWARD POSTURES RESULTING FROM THE USE OF SMARTPHONES
Background: Forward head posture is very common nowadays. Just look at anyone who works at a desk, students, or anyone who spends the majority of their day looking at some electronic device. Most of the time their head i...
SODIUM AZIDE INDUCED MUTAGENESIS IN WHEAT PLANT
Sodium azide, a chemical mutagen has become important tool to enhance agronomic traits of crop plants. It is being used to produce resistance in various susceptible crops to improve their yield and quality traits against...
MULTI DRUG RESISTANT BACTERIA ISOLATED FROM UNPASTEURIZED COW MILK FOR NUNU PRODUCTION
Unpasteurized dairy products such as Nunu and Fura de Nunu plays an important role in the dissemination of food borne diseases. Antibiotic resistance has prolonged the treatment of diseases recently. Antimicrobial suscep...