The effect of the pooling method on the live birth rate in poor ovarian responders according to the Bologna criteria
Journal Title: UNKNOWN - Year 2018, Vol 19, Issue 1
Abstract
Objective: Pooling is an alternative method to achieve in vitro fertilization outcomes. This study was to investigate the effect of pooling method on pregnancy outcomes in poor responder patients according to Bologna criteria. Materials and Methods: Two hundred-fifty five poor responder patients were enrolled in this study. Pooling embryo transfer (ET) group had 110 and fresh ET group had 145 patients. Results: Although, age was similar between both treatment groups (p=0.31), antral follicle count (p<0.001), total number of retrieved oocyte (p<0.001), total metaphase II oocyte count (p<0.001), number of stimulation cycles (p<0.001), were significantly different between the groups. The day of ET were similiar between two groups (p=0.72) but the number of ET procedure was significantly higher in pooling ET group compared to fresh ET (p<0.001). Positive pregnancy test [35/110 (32%) vs 53/145 (37%)] (p=0.43) and clinical pregnacy rates [31/110 (28%) vs 49/145 (34%)] (p=0.33) were similar between groups, whereas, implantation [31/191 (16%) vs 49/198 (25%)] (p=0.03) and live birth rates [15/110 (14%) vs 36/145 (25%)] (p=0.04) were significantly higher in fresh ET group. Despite that, abortion rates were significantly higher in pooling ET group [16/31 (52%) vs 13/49 (27%)] (p=0.04). Binary logistic regression analyese has revealed no effect of variables on live birth rates. Conclusion: Even though, pooling strategy seems to have a slight positive effect on pregnancy outcomes, there is no benefical effect on live birth rates. Furthermore, this strategy is increasing the abortion rates in parallel with clinical pregnancy rates.
Authors and Affiliations
Serdar Çelik, Niyazi Emre Turgut, Dilek Cengiz Çelik, Kübra Boynukalın, Remzi Abalı, Sevim Purisa, Erbil Yağmur, Mustafa Bahçeci
Keywords
Related Articles
- EP ID EP365264
- DOI 10.4274/tjod.62447
- Views 35
- Downloads 0
Outcome after prenatal diagnosis of fetal urinary tract abnormalities: A tertiary center experience
Objective: With the widespread use of ultrasonography for fetal screening, the detection and management of congenital urinary tract abnormalities has become crucial. In this study, we aimed to describe the clinical appro...
Current management of gynecologic cancer in pregnancy
Cancer during pregnancy is a particularly challenging complication. The incidence has increased in recent years due to childbearing at advanced maternal ages due to career choices and/or the development of reproductive t...
Erratum
DOI: 10.4274/jtgga.2017.0115 Kurdoğlu Z, Carr D, Harmouche J, Ünlü S, Kılıç GS. Short-term results of the efficacy of percutaneous tibial nerve stimulation on urinary symptoms and its financial cost. J Turk Ger Gynecol...
DHEA supplementation improves endometrial HOXA-10 mRNA expression in poor responders
Objective The study was planned to investigate whether DHEA supplementation had an impact on endometrial receptivity in women who were poor responders (POR). Materials and Methods Twenty-eight POR women who were undergo...
In patients with advanced ovarian cancer, primary suboptimal surgery has better survival outcome than interval suboptimal surgery
Objective: It is known that optimal or complete cytoreduction is the most important factor in patients with advanced ovarian cancer. The aim of this study was to examine the results of patients who did not undergo optima...