The effect of Wrightia tinctoria leaves on behavioral health
Journal Title: International Journal of Research in Pharmacology & Pharmacotherapeutics (IJRPP) - Year 2019, Vol 8, Issue 2
Abstract
The study has been designed to get better understanding about the actions of aqueous, alcohol extract and crude powder of Wrightia tinctoria leaves on the behavioral health of wistar albino rat. Spontaneous motor activity of Wistar albino rats, Motor coordination in rats, Assessment of learning and memory in rats. The animals were divided into 4 groups, each group with 6 animals. Following is the treatment allocation for the groups: Group –I control group 1.0 ml-distilled water (vehicle) was administered Group –II was administered aqueous extract (200 mg/kg ) in 1.0 ml of vehicle. Group -III was administered leaf powder (500mg/kg ) in 1.0 ml of vehicle. Group -IV was administered alcohol extract (200 mg/kg ) in 1.0 ml of vehicle. The data obtained were assessed for their statistical significance by using the tukey’s test of one-way ANOVA. There is no statistical significant difference (p<0.005) occurs between control and study groups in all the three parameters under study. No significant alteration has been noticed in the motor activity of the animals subjected to treatment with the test substances as indicated by the results of the photoactometer analysis. Similarly motor coordination has been found to be unaltered following treatment with the leaf powder or extracts under investigation. Treatment with leaf extract or powder did not alter learning and memory in rats as indicated by the results of the maze test. Absence of any alteration in the behavioral parameters are indicative of lack of CNS influence by the plant.
Authors and Affiliations
Dr. Naiyna Mohamed M. D
Keywords
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