The effects of early low dose exposures to the Environmental Estrogen Bisphenol A on the Development of Childhood Asthma
Journal Title: Archives of Asthma, Allergy and Immunology - Year 2017, Vol 1, Issue 1
Abstract
Exposure to environmental chemicals is a potential cause for the rapid increase in the prevalence of allergic asthma over the last few decades. The production of the environmental estrogen bisphenol A, the monomer of polycarbonate plastics, has increased rapidly over the last 50 years, such that bisphenol A is one of the most highly produced chemicals. It is detectable in the urine of the vast majority of the human population. While the relationship between the increase of bisphenol A in our environment and the prevalence of asthma does not prove a cause and effect relationship, it provides a strong rationale for experiments that have tested the hypothesis. Because of its small molecular size and hydrophobicity, bisphenol A is easily transferred from the mother to the fetus, via the placenta and in breast milk.
Authors and Affiliations
TM Horiuti, RM Goldblum
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