The Endothelium Dysfunction as a Possible Promoter of Development of Non-Functional Pituitary Adenoma
Journal Title: Міжнародний ендокринологічний журнал - Year 2015, Vol 6, Issue 70
Abstract
Recently the term of endothelial dysfunction has obtained a wide circulation in clinical neuroendocrinology. The phenomenon plays a significant role in genesis of many cerebrovascular brain pathological conditions. In most studies it is used as a synonym for imbalance of endothelial synthesis of NO, a signaling factor participating in mediation of its function. NO is able both to inhibit and activate apoptosis, to enhance angiogenesis and neoangiogenesis as well as to increase proliferation level and tumor cell metastasis. The review considers a possible pathogenetic role of endothelial dysfunction in non-functional pituitary adenoma development.
Authors and Affiliations
Z. Yu. Khalimova, D. Sh. Kholova, Yu. M. Urmanova, D. A. Alieva, G. A. Alimukhamedova
Keywords
Related Articles
- EP ID EP219436
- DOI -
- Views 59
- Downloads 0
Association of 5’AMP-activated protein kinase activity with disease duration and HbA1c content in leukocytes in diabetic patients
Background. 5’AMP-activated protein kinase (AMPK) is an enzyme that controls the cell energy balance. With energetic stress in the cell and an increase in the AMP concentration, ATP is replaced by AMP in the exchange ce...
Male hypogonadism (part 2)
The second part of the review shows the current approaches to the methods of diagnosis and treatment of various forms of hypogonadism in men.
Prevalence of Lipid Metabolism Disorders in the Urban Population of Ukraine Depending on the Degree and Type of Obesity
The objective of this study was subanalysis of the prevalence of lipid metabolism disorders among a cohort of respondents with overweight and obesity depending on the degree and type of obesity in a large population dete...
Hypothyroidism and pregnancy: new recommendations on the features of the diagnosis and treatment modality
The pathology of the thyroid gland is quite common, especially in iodine deficiency regions, which include Ukraine. The probability of finding violations of the functional state of the thyroid gland in pregnant women is...
The abstracts of research-to-practice conference with scientific participation “Endocrine and Neurological Diseases: Problems of Comorbidities” (September 13–14, 2018, Chernivtsi city)
.